Articles
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Citation: Implementation Science 2024 19(Suppl 1):21
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Correction: Assessing the impact of public funding in alleviating participant reduction and improving the retention rate in methadone maintenance treatment clinics in Taiwan: an interrupted time series analysis
Citation: Implementation Science 2024 19:28 -
Generative AI in healthcare: an implementation science informed translational path on application, integration and governance
Artificial intelligence (AI), particularly generative AI, has emerged as a transformative tool in healthcare, with the potential to revolutionize clinical decision-making and improve health outcomes. Generativ...
Citation: Implementation Science 2024 19:27 -
Navigating the field of implementation science towards maturity: challenges and opportunities
The field of implementation science has significantly expanded in size and scope over the past two decades, although work related to understanding implementation processes have of course long preceded the more...
Citation: Implementation Science 2024 19:26 -
Comparative effectiveness of implementation strategies for Accelerating Cervical Cancer Elimination through the integration of Screen-and-treat Services (ACCESS study): protocol for a cluster randomized hybrid type III trial in Nigeria
Despite the increased risk of cervical cancer (CC) among women living with HIV (WLHIV), CC screening and treatment (CCST) rates remain low in Africa. The integration of CCST services into established HIV progr...
Citation: Implementation Science 2024 19:25 -
Evidence-based Medication knowledge Brokers in Residential Aged CarE (EMBRACE): protocol for a helix-counterbalanced randomised controlled trial
Clinical practice guidelines recommend against the routine use of psychotropic medications in residential aged care facilities (RACFs). Knowledge brokers are individuals or groups who facilitate the transfer o...
Citation: Implementation Science 2024 19:24 -
Protocol for a parallel cluster randomized trial of a participatory tailored approach to reduce overuse of antibiotics at hospital discharge: the ROAD home trial
Antibiotic overuse at hospital discharge is common, costly, and harmful. While discharge-specific antibiotic stewardship interventions are effective, they are resource-intensive and often infeasible for hospit...
Citation: Implementation Science 2024 19:23 -
Organize and mobilize for implementation effectiveness to improve overdose education and naloxone distribution from syringe services programs: a randomized controlled trial
The United States (US) continues to face decades-long increases in opioid overdose fatalities. As an opioid overdose reversal medication, naloxone can dramatically reduce opioid overdose mortality rates when d...
Citation: Implementation Science 2024 19:22 -
Implementation strategies in suicide prevention: a scoping review
Implementation strategies can be a vital leveraging point for enhancing the implementation and dissemination of evidence-based suicide prevention interventions and programming. However, much remains unknown ab...
Citation: Implementation Science 2024 19:20 -
Protocol for the ONLOOP trial: pragmatic randomized trial evaluating a province-wide system of personalized reminders for evidence-based surveillance tests in adult survivors of childhood cancer in Ontario
Childhood cancer treatment while often curative, leads to elevated risks of morbidity and mortality. Survivors require lifelong periodic surveillance for late effects of treatment, yet adherence to guideline-r...
Citation: Implementation Science 2024 19:19 -
Assessing the impact of public funding in alleviating participant reduction and improving the retention rate in methadone maintenance treatment clinics in Taiwan: an interrupted time series analysis
Given the steady decline in patient numbers at methadone maintenance treatment (MMT) clinics in Taiwan since 2013, the government initiated Patients’ Medical Expenditure Supplements (PMES) in January 2019 and...
Citation: Implementation Science 2024 19:18 -
Leveraging artificial intelligence to advance implementation science: potential opportunities and cautions
The field of implementation science was developed to address the significant time delay between establishing an evidence-based practice and its widespread use. Although implementation science has contributed m...
Citation: Implementation Science 2024 19:17 -
Sustaining the collaborative chronic care model in outpatient mental health: a matrixed multiple case study
Sustaining evidence-based practices (EBPs) is crucial to ensuring care quality and addressing health disparities. Approaches to identifying factors related to sustainability are critically needed. One such app...
Citation: Implementation Science 2024 19:16 -
‘It depends’: what 86 systematic reviews tell us about what strategies to use to support the use of research in clinical practice
The gap between research findings and clinical practice is well documented and a range of strategies have been developed to support the implementation of research into clinical practice. The objective of this ...
Citation: Implementation Science 2024 19:15 -
Implementation of state health insurance benefit mandates for cancer-related fertility preservation: following policy through a complex system
A myriad of federal, state, and organizational policies are designed to improve access to evidence-based healthcare, but the impact of these policies likely varies due to contextual determinants of, reinterpre...
Citation: Implementation Science 2024 19:14 -
Specifying cross-system collaboration strategies for implementation: a multi-site qualitative study with child welfare and behavioral health organizations
Cross-system interventions that integrate health, behavioral health, and social services can improve client outcomes and expand community impact. Successful implementation of these interventions depends on the...
Citation: Implementation Science 2024 19:13 -
Implicit and explicit: a scoping review exploring the contribution of anthropological practice in implementation science
This study’s goal is to identify the existing variation in how, why, and by whom anthropological practice is conducted as part of implementation science projects. As doctorally trained anthropologists, we soug...
Citation: Implementation Science 2024 19:12 -
Exploring the role of professional identity in the implementation of clinical decision support systems—a narrative review
Clinical decision support systems (CDSSs) have the potential to improve quality of care, patient safety, and efficiency because of their ability to perform medical tasks in a more data-driven, evidence-based, ...
Citation: Implementation Science 2024 19:11 -
Adjunctive interventions: change methods directed at recipients that support uptake and use of health innovations
Implementation science groups change methods into two categories: (1) clinical, behavioral, or biomedical intervention targeting recipient’s health outcomes and (2) implementation strategies targeting the deliver...
Citation: Implementation Science 2024 19:10 -
Action planning for building public health program sustainability: results from a group-randomized trial
Public health programs are charged with implementing evidence-based interventions to support public health improvement; however, to achieve long-term population-based benefits, these interventions must be sust...
Citation: Implementation Science 2024 19:9 -
The effectiveness of interventions to disseminate the results of non-commercial randomised clinical trials to healthcare professionals: a systematic review
It is unclear how to disseminate the results of randomised controlled trials effectively to health professionals and policymakers to improve treatment, care or prevention through changing policy and practice. ...
Citation: Implementation Science 2024 19:8 -
Models and approaches for building knowledge translation capacity and capability in health services: a scoping review
Building healthcare service and health professionals’ capacity and capability to rapidly translate research evidence into health practice is critical to the effectiveness and sustainability of healthcare syste...
Citation: Implementation Science 2024 19:7 -
Conditions for adherence to videoconference-based programs promoting adapted physical activity in cancer patients: a realist evaluation
Although moderate physical activity (PA) during cancer treatment has been associated with improved quality of life, reduced side effects, and even lower mortality, many barriers to successful implementation re...
Citation: Implementation Science 2024 19:6 -
Tailored implementation of national recommendations on fall prevention among older adults in municipalities in Norway (FALLPREVENT trial): a study protocol for a cluster-randomised trial
Despite substantial research evidence indicating the effectiveness of a range of interventions to prevent falls, uptake into routine clinical practice has been limited by several implementation challenges. The...
Citation: Implementation Science 2024 19:5 -
Implementation fidelity, student outcomes, and cost-effectiveness of train-the-trainer strategies for Masters-level therapists in urban schools: results from a cluster randomized trial
Little is known about the effectiveness and cost-effectiveness of train-the-trainer implementation strategies in supporting mental health evidence-based practices in schools, and about the optimal level of sup...
Citation: Implementation Science 2024 19:4 -
Influence of physician networks on the implementation of pharmaceutical alternatives to a toxic drug supply in British Columbia
Characterizing the diffusion of adopted changes in policy and clinical practice can inform enhanced implementation strategies to ensure prompt uptake in public health emergencies and other rapidly evolving dis...
Citation: Implementation Science 2024 19:3 -
Protocol for a hybrid type 3 effectiveness-implementation trial of a pragmatic individual-level implementation strategy for supporting school-based prevention programming
For approximately one in five children who have social, emotional, and behavioral (SEB) challenges, accessible evidence-based prevention practices (EBPPs) are critical. In the USA, schools are the primary sett...
Citation: Implementation Science 2024 19:2 -
Cluster-randomized implementation trial of two facilitation strategies to implement a novel information and communications technology at the Veterans Health Administration
Information and communication technologies (ICTs) improve quality and efficiency of healthcare, but effective practices for implementing new ICTs are unknown. From 2019 to 2021, the Veterans Health Administrat...
Citation: Implementation Science 2024 19:1 -
Correction: Identifying behaviour change techniques in 287 randomized controlled trials of audit and feedback interventions targeting practice change among healthcare professionals
Citation: Implementation Science 2023 18:73 -
Addressing COVID-19 vaccine hesitancy in rural community pharmacies: a protocol for a stepped wedge randomized clinical trial
Uptake of COVID-19 vaccines remains problematically low in the USA, especially in rural areas. COVID-19 vaccine hesitancy is associated with lower uptake, which translates to higher susceptibility to SARS-CoV-...
Citation: Implementation Science 2023 18:72 -
Audit and feedback to reduce unwarranted clinical variation at scale: a realist study of implementation strategy mechanisms
Unwarranted clinical variation in hospital care includes the underuse, overuse, or misuse of services. Audit and feedback is a common strategy to reduce unwarranted variation, but its effectiveness varies wide...
Citation: Implementation Science 2023 18:71 -
Alarm with care—a de-implementation strategy to reduce fall prevention alarm use in US hospitals: a study protocol for a hybrid 2 effectiveness-implementation trial
Fall prevention alarms are commonly used among US hospitals as a fall prevention strategy despite limited evidence of effectiveness. Further, fall prevention alarms are harmful to healthcare staff (e.g., alarm...
Citation: Implementation Science 2023 18:70 -
Knowledge translation strategies to support the sustainability of evidence-based interventions in healthcare: a scoping review
Knowledge translation (KT) strategies are widely used to facilitate the implementation of EBIs into healthcare practices. However, it is unknown what and how KT strategies are used to facilitate the sustainabi...
Citation: Implementation Science 2023 18:69 -
Factors influencing implementation of a care coordination intervention for cancer survivors with multiple comorbidities in a safety-net system: an application of the Implementation Research Logic Model
Under- and uninsured cancer survivors have significant medical, social, and economic complexity. For these survivors, effective care coordination between oncology and primary care teams is critical for high-qu...
Citation: Implementation Science 2023 18:68 -
Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficient cluster randomised controlled trial using the OpenSAFELY platform
Germ Defence (www.​germdefence.​org) is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximi...
Citation: Implementation Science 2023 18:67 -
Results of a cluster randomized trial testing the Systems Analysis and Improvement Approach to increase cervical cancer screening in family planning clinics in Mombasa County, Kenya
Cervical cancer is the leading cause of cancer death in Kenyan women. Integrating cervical cancer screening into family planning (FP) clinics is a promising strategy to improve health for reproductive-aged wom...
Citation: Implementation Science 2023 18:66 -
Protocol for a pragmatic stepped wedge cluster randomized clinical trial testing behavioral economic implementation strategies to increase supplemental breast MRI screening among patients with extremely dense breasts
Increased breast density augments breast cancer risk and reduces mammography sensitivity. Supplemental breast MRI screening can significantly increase cancer detection among women with dense breasts. However, ...
Citation: Implementation Science 2023 18:65 -
Design of a dual randomized trial in a type 2 hybrid effectiveness—implementation study
Dual randomized controlled trials (DRCT) are type 2 hybrid studies that include two randomized trials: one testing implementation strategies and one testing an intervention. We argue that this study design off...
Citation: Implementation Science 2023 18:64 -
Identifying behaviour change techniques in 287 randomized controlled trials of audit and feedback interventions targeting practice change among healthcare professionals
Audit and feedback (A&F) is among the most widely used implementation strategies, providing healthcare professionals with summaries of their practice performance to prompt behaviour change and optimize care. W...
Citation: Implementation Science 2023 18:63 -
Built to last? Barriers and facilitators of healthcare program sustainability: a systematic integrative review
To identify barriers and facilitators associated with the sustainability of implemented and evaluated improvement programs in healthcare delivery systems.
Citation: Implementation Science 2023 18:62 -
External context in individual placement and support implementation: a scoping review with abductive thematic analysis
Context including the external context may considerably affect the adoption, implementation, sustainment, and scale-up of evidence-based practices. We investigated external contextual features by conducting a ...
Citation: Implementation Science 2023 18:61 -
Implementation and dissemination of home- and community-based interventions for informal caregivers of people living with dementia: a systematic scoping review
Informal caregivers of people with dementia (PwD) living at home are often the primary source of care, and, in their role, they often experience loss of quality of life. Implementation science knowledge is nee...
Citation: Implementation Science 2023 18:60 -
Top-level leaders and implementation strategies to support organizational diversity, equity, inclusion, and belonging (DEIB) interventions: a qualitative study of top-level DEIB leaders in healthcare organizations
The Black Lives Matter movement and COVID-19 pandemic motivated the wide-scale adoption of diversity, equity, inclusion, and belonging (DEIB) initiatives within healthcare organizations and the creation of DEI...
Citation: Implementation Science 2023 18:59 -
Revisiting the policy ecology framework for implementation of evidence-based practices in mental health settings
Over the past three decades, policy actors and actions have been highly influential in supporting the implementation of evidence-based practices (EBPs) in mental health settings. An early examination of these ...
Citation: Implementation Science 2023 18:58 -
Protocol to evaluate sequential electronic health record-based strategies to increase genetic testing for breast and ovarian cancer risk across diverse patient populations in gynecology practices
Germline genetic testing is recommended by the National Comprehensive Cancer Network (NCCN) for individuals including, but not limited to, those with a personal history of ovarian cancer, young-onset (< 50 yea...
Citation: Implementation Science 2023 18:57 -
Application of the Expert Recommendations for Implementing Change (ERIC) compilation of strategies to health intervention implementation in low- and middle-income countries: a systematic review
The Expert Recommendations for Implementing Change (ERIC) project developed a compilation of implementation strategies that are intended to standardize reporting and evaluation. Little is known about the appli...
Citation: Implementation Science 2023 18:56 -
Supporting translation of research evidence into practice—the use of Normalisation Process Theory to assess and inform implementation within randomised controlled trials: a systematic review
The status of randomised controlled trials (RCTs) as the ‘gold standard’ for evaluating efficacy in healthcare interventions is increasingly debated among the research community, due to often insufficient cons...
Citation: Implementation Science 2023 18:55 -
Sustainability, spread, and scale in trials using audit and feedback: a theory-informed, secondary analysis of a systematic review
Audit and feedback (A&F) is a widely used implementation strategy to influence health professionals’ behavior that is often tested in implementation trials. This study examines how A&F trials describe sustaina...
Citation: Implementation Science 2023 18:54 -
Correction: Ten years of implementation outcomes research: a scoping review
Citation: Implementation Science 2023 18:53 -
Eight characteristics of rigorous multilevel implementation research: a step-by-step guide
Although healthcare is delivered in inherently multilevel contexts, implementation science has no widely endorsed methodological standards defining the characteristics of rigorous, multilevel implementation re...
Citation: Implementation Science 2023 18:52
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