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  1. Experts recommend that treatment for substance use disorder (SUD) be integrated into primary care. The Digital Therapeutics for Opioids and Other SUD (DIGITS) Trial tests strategies for implementing reSET® and...

    Authors: Joseph E. Glass, Caitlin N. Dorsey, Tara Beatty, Jennifer F. Bobb, Edwin S. Wong, Lorella Palazzo, Deborah King, Jessica Mogk, Kelsey Stefanik-Guizlo, Abisola Idu, Dustin Key, John C. Fortney, Rosemarie Thomas, Angela Garza McWethy, Ryan M. Caldeiro and Katharine A. Bradley
    Citation: Implementation Science 2023 18:3
    Content type: Study protocol Published on:

  2. Facilitated implementation of nurse-initiated protocols to manage fever, hyperglycaemia (sugar) and swallowing difficulties (FeSS Protocols) in 19 Australian stroke units resulted in reduced death and dependen...

    Authors: O. Fasugba, S. Dale, E. McInnes, D. A. Cadilhac, M. Noetel, K. Coughlan, B. McElduff, J. Kim, T. Langley, N. W. Cheung, K. Hill, V. Pollnow, K. Page, E. Sanjuan Menendez, E. Neal, S. Griffith…
    Citation: Implementation Science 2023 18:2
    Content type: Study protocol Published on:

  3. Postpartum haemorrhage (PPH) is the leading cause of global maternal deaths, accounting for 30–50% of maternal deaths in sub-Saharan Africa. Most PPH-related deaths are preventable with timely detection and in...

    Authors: Gillian Forbes, Shahinoor Akter, Suellen Miller, Hadiza Galadanci, Zahida Qureshi, Sue Fawcus, G. Justus Hofmeyr, Neil Moran, Mandisa Singata-Madliki, Faisal Dankishiya, George Gwako, Alfred Osoti, Eleanor Thomas, Ioannis Gallos, Kristie-Marie Mammoliti, Adam Devall…
    Citation: Implementation Science 2023 18:1
    Content type: Research Published on:

  4. The journals Implementation Science and Implementation Science Communications are focused on the implementation of evidence into healthcare practice and policy. This editorial offers reflections on how we handle ...

    Authors: Michel Wensing, Anne Sales, Gregory A. Aarons, Dong (Roman) Xu and Paul Wilson
    Citation: Implementation Science 2022 17:83
    Content type: Editorial Published on:

  5. Evidence-based practices (EBPs) for patients receiving invasive mechanical ventilation vary in the quality of their underlying evidence and ease of implementation.

    Authors: Jennifer N. Ervin, Millie R. Dibble, Victor C. Rentes, Michael W. Sjoding, Michelle N. Gong, Catherine L. Hough, Theodore J. Iwashyna and Anne E. Sales
    Citation: Implementation Science 2022 17:82
    Content type: Short report Published on:

  6. Sustainability is concerned with the long-term delivery and subsequent benefits of evidence-based interventions. To further this field, we require a strong understanding and thus measurement of sustainability ...

    Authors: Alix Hall, Adam Shoesmith, Emma Doherty, Brydie McEvoy, Kayne Mettert, Cara C. Lewis, Luke Wolfenden, Serene Yoong, Melanie Kingsland, Rachel C. Shelton, Shannon Wiltsey Stirman, Noor Imad, Rachel Sutherland and Nicole Nathan
    Citation: Implementation Science 2022 17:81
    Content type: Systematic review Published on:

  7. Implementation science aims to accelerate the public health impact of evidence-based interventions. However, implementation science has had too little focus on the role of health policy — and its inseparable p...

    Authors: Erika L. Crable, Rebecca Lengnick-Hall, Nicole A. Stadnick, Joanna C. Moullin and Gregory A. Aarons
    Citation: Implementation Science 2022 17:80
    Content type: Debate Published on:

  8. Smoking during pregnancy is the most important preventable cause of adverse pregnancy outcomes, yet smoking cessation support (SCS) is inconsistently provided. The MOMHQUIT intervention was developed to addres...

    Authors: Larisa Ariadne Justine Barnes, Jo Longman, Catherine Adams, Christine Paul, Lou Atkins, Billie Bonevski, Aaron Cashmore, Laura Twyman, Ross Bailie, Alison Pearce, Daniel Barker, Andrew J. Milat, Julie Dorling, Michael Nicholl and Megan Passey
    Citation: Implementation Science 2022 17:79
    Content type: Study protocol Published on:

  9. The number of research publications reporting the use of the Promoting Action on Research Implementation in Health Services (PARIHS) framework and the integrated PARIHS (i-PARIHS) framework has grown steadily....

    Authors: Yinfei Duan, Alba Iaconi, Jing Wang, Janelle Santos Perez, Yuting Song, Stephanie A. Chamberlain, Shovana Shrestha, Katharina Choroschun, Matthias Hoben, Anna Beeber, Ruth A. Anderson, Greta G. Cummings, Holly J. Lanham, Peter G. Norton, Carole A. Estabrooks and Whitney Berta
    Citation: Implementation Science 2022 17:78
    Content type: Systematic review Published on:

  10. Opioids can be effective analgesics, but long-term use may be associated with harms. In 2013, the first national, comprehensive, evidence-based pain management guideline was published, from the Scottish Interc...

    Authors: Harry L. Hébert, Daniel R. Morales, Nicola Torrance, Blair H. Smith and Lesley A. Colvin
    Citation: Implementation Science 2022 17:77
    Content type: Research Published on:

  11. Historically, the focus of cost-effectiveness analyses has been on the costs to operate and deliver interventions after their initial design and launch. The costs related to design and implementation of interv...

    Authors: Akash Malhotra, Ryan R. Thompson, Faith Kagoya, Felix Masiye, Peter Mbewe, Mosepele Mosepele, Jane Phiri, Jairos Sambo, Abigail Barker, Drew B. Cameron, Victor G. Davila-Roman, William Effah, Brian Hutchinson, Michael Laxy, Brad Newsome, David Watkins…
    Citation: Implementation Science 2022 17:76
    Content type: Systematic review Published on:

  12. Many implementation efforts fail, even with highly developed plans for execution, because contextual factors can be powerful forces working against implementation in the real world. The Consolidated Framework ...

    Authors: Laura J. Damschroder, Caitlin M. Reardon, Marilla A. Opra Widerquist and Julie Lowery
    Citation: Implementation Science 2022 17:75
    Content type: Research Published on:

  13. Clinical guideline development often involves a rigorous synthesis of evidence involving multidisciplinary stakeholders with different priorities and knowledge of evidence synthesis; this makes communicating f...

    Authors: Melissa K. Sharp, Dayang Anis Binti Awang Baki, Joan Quigley, Barrie Tyner, Declan Devane, Kamal R. Mahtani, Susan M. Smith, Michelle O’Neill, Máirín Ryan and Barbara Clyne
    Citation: Implementation Science 2022 17:74
    Content type: Systematic review Published on:

  14. The use of low-value care (LVC) is a persistent problem that calls for knowledge about strategies for de-implementation. However, studies are dispersed across many clinical fields, and there is no overview of ...

    Authors: Sara Ingvarsson, Henna Hasson, Ulrica von Thiele Schwarz, Per Nilsen, Byron J. Powell, Clara Lindberg and Hanna Augustsson
    Citation: Implementation Science 2022 17:73
    Content type: Research Published on:

  15. Methods of sustaining the deimplementation of overused medical practices (i.e., practices not supported by evidence) are understudied. In pediatric hospital medicine, continuous pulse oximetry monitoring of ch...

    Authors: Christopher P. Bonafide, Rui Xiao, Amanda C. Schondelmeyer, Amy R. Pettit, Patrick W. Brady, Christopher P. Landrigan, Courtney Benjamin Wolk, Zuleyha Cidav, Halley Ruppel, Naveen Muthu, Nathaniel J. Williams, Enrique Schisterman, Canita R. Brent, Kimberly Albanowski and Rinad S. Beidas
    Citation: Implementation Science 2022 17:72
    Content type: Study protocol Published on:

  16. Tailored implementation approaches are touted as superior to standardized ones with the reasoning that tailored approaches afford opportunities to select strategies to resolve determinants of the local context...

    Authors: Cara C. Lewis, Meredith R. Boyd, C. Nathan Marti and Karen Albright
    Citation: Implementation Science 2022 17:71
    Content type: Research Published on:

  17. In Kenya, HIV incidence is highest among reproductive-age women. A key HIV mitigation strategy is the integration of HIV testing and counseling (HTC) into family planning services, but successful integration r...

    Authors: Jessica E. Long, McKenna C. Eastment, George Wanje, Barbra A. Richardson, Emily Mwaringa, Mwanakarama Athman Mohamed, Kenneth Sherr, Ruanne V. Barnabas, Kishorchandra Mandaliya, Walter Jaoko and R. Scott McClelland
    Citation: Implementation Science 2022 17:70
    Content type: Research Published on:

  18. The rational use of antibiotics is of great importance in health care. In primary care, acute respiratory infections are the most common cause of inappropriate antibiotic prescribing. Since existing studies ai...

    Authors: Christin Löffler, Theresa Buuck, Julia Iwen, Maike Schulz, Antonia Zapf, Peter Kropp, Anja Wollny, Linda Krause, Britta Müller, Ann-Katrin Ozga, Elisabeth Goldschmidt and Attila Altiner
    Citation: Implementation Science 2022 17:69
    Content type: Study protocol Published on:

  19. Natural disasters and public health crises can disrupt communities’ capacities to implement important public health programs. A nationwide implementation of an evidence-based HIV prevention program, Focus on Y...

    Authors: Lynette Deveaux, Elizabeth Schieber, Lesley Cottrell, Regina Firpo-Triplett, Richard Adderley, Karen MacDonell, Nikkiah Forbes and Bo Wang
    Citation: Implementation Science 2022 17:68
    Content type: Research Published on:

  20. The Veterans Health Administration (VA) Grant and Per Diem case management “aftercare” program provides 6 months of case management for homeless-experienced veterans (HEVs) undergoing housing transitions. To s...

    Authors: Sonya Gabrielian, Erin P. Finley, David A. Ganz, Jenny M. Barnard, Nicholas J. Jackson, Ann Elizabeth Montgomery, Richard E. Nelson and Kristina M. Cordasco
    Citation: Implementation Science 2022 17:67
    Content type: Study protocol Published on:

  21. Statistical tests of mediation are important for advancing implementation science; however, little research has examined the sample sizes needed to detect mediation in 3-level designs (e.g., organization, prov...

    Authors: Nathaniel J. Williams, Kristopher J. Preacher, Paul D. Allison, David S. Mandell and Steven C. Marcus
    Citation: Implementation Science 2022 17:66
    Content type: Research Published on:

  22. Healthcare costs are rising, and a substantial proportion of medical care is of little value. De-implementation of low-value practices is important for improving overall health outcomes and reducing costs. We ...

    Authors: Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette…
    Citation: Implementation Science 2022 17:65
    Content type: Systematic review Published on:

  23. In response to the US opioid epidemic, significant national campaigns have been launched to expand access to `opioid use disorder (MOUD). While adoption has increased in general medical care settings, specialt...

    Authors: James H. Ford II, Hannah Cheng, Michele Gassman, Harrison Fontaine, Hélène Chokron Garneau, Ryan Keith, Edward Michael and Mark P. McGovern
    Citation: Implementation Science 2022 17:64
    Content type: Study protocol Published on:

  24. For people living with dementia (PLWD) the overuse of potentially inappropriate medications (PIMs) remains a persistent problem. De-prescribing trials in the elderly have mixed results. Clinician champions may...

    Authors: Michael L. Parchman, Jennifer Perloff and Grant Ritter
    Citation: Implementation Science 2022 17:63
    Content type: Study protocol Published on:

  25. The Practical, Robust Implementation and Sustainability Model (PRISM) was developed in 2008 as a contextually expanded version of the broadly used Reach, Adoption, Effectiveness, Implementation, and Maintenanc...

    Authors: Borsika A. Rabin, Julie Cakici, Caitlin A. Golden, Paul A. Estabrooks, Russell E. Glasgow and Bridget Gaglio
    Citation: Implementation Science 2022 17:62
    Content type: Systematic review Published on:

  26. Authors: Aaron M. Woolsey, Ryan A. Simmons, Meley Woldeghebriel, Yunji Zhou, Oluwatosin Ogunsola, Sarah Laing, Tayo Olaleye, Joseph Kipkoech, Bomar Mendez Rojas, Indrani Saran, Mercy Odhiambo, Josephine Malinga, George Ambani, Emmah Kimachas, Chizoba Fashanu, Owens Wiwa…
    Citation: Implementation Science 2022 17:61
    Content type: Correction Published on:

    The original article was published in Implementation Science 2021 16:14

  27. Reducing the rate of stillbirth is an international priority. At least half of babies stillborn in high-income countries are small for gestational-age (SGA). The Growth Assessment Protocol (GAP), a complex ant...

    Authors: Sophie Relph, Kirstie Coxon, Matias C. Vieira, Andrew Copas, Andrew Healey, Alessandro Alagna, Annette Briley, Mark Johnson, Deborah A. Lawlor, Christoph Lees, Neil Marlow, Lesley McCowan, Jessica McMicking, Louise Page, Donald Peebles, Andrew Shennan…
    Citation: Implementation Science 2022 17:60
    Content type: Research Published on:

  28. This study will explore implementation mechanisms through which a single implementation strategy and a multifaceted implementation strategy operate to affect the implementation outcome, which is fidelity to the G...

    Authors: Lydia Kwak, Anna Toropova, Byron J. Powell, Rebecca Lengnick-Hall, Irene Jensen, Gunnar Bergström, Liselotte Schäfer Elinder, Kjerstin Stigmar, Charlotte Wåhlin and Christina Björklund
    Citation: Implementation Science 2022 17:59
    Content type: Study protocol Published on:

  29. Implementation Mapping is an organized method to select implementation strategies. However, there are 73 Expert Recommendations for Implementing Change (ERIC) strategies. Thus, it is difficult for implementati...

    Authors: Florian R. Schroeck, A. Aziz Ould Ismail, David A. Haggstrom, Steven L. Sanchez, DeRon R. Walker and Lisa Zubkoff
    Citation: Implementation Science 2022 17:58
    Content type: Methodology Published on:

  30. Evidence-based interventions that optimize physical function for disabled and older adults living in the community who have difficulty with daily living tasks are available. However, uptake has been limited, p...

    Authors: Sandra L. Spoelstra, Monica Schueller, Viktoria Basso and Alla Sikorskii
    Citation: Implementation Science 2022 17:57
    Content type: Research Published on:

  31. Efforts to generate evidence for implementation strategies are frustrated by insufficient description. The Expert Recommendations for Implementing Change (ERIC) compilation names and defines implementation str...

    Authors: Sheena McHugh, Justin Presseau, Courtney T. Luecking and Byron J. Powell
    Citation: Implementation Science 2022 17:56
    Content type: Research Published on:

  32. Implementation science is at a sufficiently advanced stage that it is appropriate for the field to reflect on progress thus far in achieving its vision, with a goal of charting a path forward. In this debate, ...

    Authors: Rinad S. Beidas, Shannon Dorsey, Cara C. Lewis, Aaron R. Lyon, Byron J. Powell, Jonathan Purtle, Lisa Saldana, Rachel C. Shelton, Shannon Wiltsey Stirman and Meghan B. Lane-Fall
    Citation: Implementation Science 2022 17:55
    Content type: Debate Published on:

  33. Authors: Shawna N. Smith, Daniel Almirall, Seo Youn Choi, Elizabeth Koschmann, Amy Rusch, Emily Bilek, Annalise Lane, James L. Abelson, Daniel Eisenberg, Joseph A. Himle, Kate D. Fitzgerald, Celeste Liebrecht and Amy M. Kilbourne
    Citation: Implementation Science 2022 17:54
    Content type: Correction Published on:

    The original article was published in Implementation Science 2022 17:42

  34. The field of dissemination and implementation (D&I) research has grown immensely in recent years. However, the field of dissemination research has not coalesced to the same degree as the field of implementatio...

    Authors: Ana A. Baumann, Cole Hooley, Emily Kryzer, Alexandra B. Morshed, Cassidy A. Gutner, Sara Malone, Callie Walsh-Bailey, Meagan Pilar, Brittney Sandler, Rachel G. Tabak and Stephanie Mazzucca
    Citation: Implementation Science 2022 17:53
    Content type: Research Published on:

  35. Implementation strategies are aimed at improving guideline adherence. Both effect and process evaluations are conducted to provide insights into the success or failure of these strategies. In our study, we eva...

    Authors: Julie E. M. Swillens, Quirinus J. M. Voorham, Reinier P. Akkermans, Iris D. Nagtegaal and Rosella P. M. G. Hermens
    Citation: Implementation Science 2022 17:52
    Content type: Research Published on:

  36. Interventions are often adapted; some adaptations may provoke more favorable outcomes, whereas some may not. A better understanding of the adaptations and their intended goals may elucidate which adaptations p...

    Authors: Jodi Summers Holtrop, Dennis Gurfinkel, Andrea Nederveld, Phoutdavone Phimphasone-Brady, Patrick Hosokawa, Claude Rubinson, Jeanette A. Waxmonsky and Bethany M. Kwan
    Citation: Implementation Science 2022 17:51
    Content type: Research Published on:

  37. Guidelines aim to support evidence-informed practice but are inconsistently used without implementation strategies. Our prior scoping review revealed that guideline implementation interventions were not select...

    Authors: Sanne Peters, Krithika Sukumar, Sophie Blanchard, Akilesh Ramasamy, Jennifer Malinowski, Pamela Ginex, Emily Senerth, Marleen Corremans, Zachary Munn, Tamara Kredo, Lucia Prieto Remon, Etienne Ngeh, Lisa Kalman, Samia Alhabib, Yasser Sami Amer and Anna Gagliardi
    Citation: Implementation Science 2022 17:50
    Content type: Systematic review Published on:

  38. Academic institutions building capacity for implementation scholarship are also well positioned to build capacity in real world health and human service settings. How practitioners and policy makers are includ...

    Authors: Lisa A. Juckett, Alicia C. Bunger, Molly M. McNett, Monica L. Robinson and Sharon J. Tucker
    Citation: Implementation Science 2022 17:49
    Content type: Systematic review Published on:

  39. Strategic implementation leadership is a critical determinant of successful implementation, hypothesized to create a more supportive implementation climate conducive to the adoption and use of evidence-based p...

    Authors: Aaron R. Lyon, Catherine M. Corbin, Eric C. Brown, Mark G. Ehrhart, Jill Locke, Chayna Davis, Elissa Picozzi, Gregory A. Aarons and Clayton R. Cook
    Citation: Implementation Science 2022 17:48
    Content type: Research Published on:

  40. Successful guideline implementation depends both on factors extrinsic to guidelines and their intrinsic features. In the Guideline Implementability for Decision Excellence Model (GUIDE-M), “communicating” cont...

    Authors: Samir Gupta, Rosalind Tang, Kadia Petricca, Ivan D. Florez and Monika Kastner
    Citation: Implementation Science 2022 17:47
    Content type: Research Published on:

  41. Participatory design methods are a key component of designing tailored implementation strategies. These methods vary in the resources required to execute and analyze their outputs. No work to date has examined...

    Authors: Emily M. Becker-Haimes, Brinda Ramesh, Jacqueline E. Buck, Heather J. Nuske, Kelly A. Zentgraf, Rebecca E. Stewart, Alison Buttenheim and David S. Mandell
    Citation: Implementation Science 2022 17:46
    Content type: Research Published on:

  42. Despite improvement, sepsis mortality rates remain high, with an estimated 11 million sepsis-related deaths globally in 2017 (Rudd et. al, Lancet 395:200-211, 2020). Low- and middle-income countries (LMICs) ar...

    Authors: Lisa M. Puchalski Ritchie, Lemlem Beza, Finot Debebe, Andualem Wubetie, Kathleen Gamble, Gerald Lebovic, Sharon E. Straus, Tigist Zewdu, Aklilu Azazh, Cheryl Hunchak, Megan Landes and Dawit Kebebe Huluka
    Citation: Implementation Science 2022 17:45
    Content type: Research Published on:

  43. The US continues to face public health crises related to both chronic pain and opioid overdoses. Thirty percent of Americans suffer from chronic noncancer pain at an estimated yearly cost of over $600 billion....

    Authors: Ramzi G. Salloum, Lori Bilello, Jiang Bian, Julie Diiulio, Laura Gonzalez Paz, Matthew J. Gurka, Maria Gutierrez, Robert W. Hurley, Ross E. Jones, Francisco Martinez-Wittinghan, Laura Marcial, Ghania Masri, Cara McDonnell, Laura G. Militello, François Modave, Khoa Nguyen…
    Citation: Implementation Science 2022 17:44
    Content type: Study protocol Published on:

  44. The USA is undergoing a suicide epidemic for its youngest Veterans (18-to-34-years-old) as their suicide rate has almost doubled since 2001. Veterans are at the highest risk during their first-year post-discha...

    Authors: Joseph C. Geraci, Erin P. Finley, Emily R. Edwards, Sheila Frankfurt, A. Solomon Kurz, Nipa Kamdar, Megan E. Vanneman, Leonard M. Lopoo, Hannah Patnaik, Jean Yoon, Nicholas Armstrong, Ashley L. Greene, Gilly Cantor, Joseph Wrobleski, Erin Young, Matthew Goldsmith…
    Citation: Implementation Science 2022 17:43
    Content type: Study protocol Published on:

  45. Schools increasingly provide mental health services to students, but often lack access to implementation strategies to support school-based (and school professional [SP]) delivery of evidence-based practices. ...

    Authors: Shawna N. Smith, Daniel Almirall, Seo Youn Choi, Elizabeth Koschmann, Amy Rusch, Emily Bilek, Annalise Lane, James L. Abelson, Daniel Eisenberg, Joseph A. Himle, Kate D. Fitzgerald, Celeste Liebrecht and Amy M. Kilbourne
    Citation: Implementation Science 2022 17:42
    Content type: Research Published on:

    The Correction to this article has been published in Implementation Science 2022 17:54

  46. Many strategies aimed at deprescribing benzodiazepine receptor agonists (BZRA) in older adults have already been evaluated with various success rates. There is so far no consensus on which strategy components ...

    Authors: Perrine Evrard, Catherine Pétein, Jean-Baptiste Beuscart and Anne Spinewine
    Citation: Implementation Science 2022 17:41
    Content type: Systematic review Published on:

  47. Internationally, government policies mandating schools to provide students with opportunities to participate in physical activity are poorly implemented. The multi-component Physically Active Children in Educatio...

    Authors: Cassandra Lane, Nicole Nathan, Penny Reeves, Rachel Sutherland, Luke Wolfenden, Adam Shoesmith and Alix Hall
    Citation: Implementation Science 2022 17:40
    Content type: Research Published on:

  48. State legislators make policy decisions that influence children’s exposure to adverse childhood experiences (ACEs), such as child maltreatment, and their effects on behavioral health. Effective dissemination o...

    Authors: Jonathan Purtle, Katherine L. Nelson, Luwam Gebrekristos, Félice Lê-Scherban and Sarah E. Gollust
    Citation: Implementation Science 2022 17:38
    Content type: Research Published on:

  49. There are increasing efforts for the integration of mental health services into primary care settings in low- and middle-income countries. However, commonly used approaches to train primary care providers (PCP...

    Authors: Brandon A. Kohrt, Elizabeth L. Turner, Dristy Gurung, Xueqi Wang, Mani Neupane, Nagendra P. Luitel, Muralikrishnan R. Kartha, Anubhuti Poudyal, Ritika Singh, Sauharda Rai, Phanindra Prasad Baral, Sabrina McCutchan, Petra C. Gronholm, Charlotte Hanlon, Heidi Lempp, Crick Lund…
    Citation: Implementation Science 2022 17:39
    Content type: Study protocol Published on:

  50. Significant investments are being made to close the mental health (MH) treatment gap, which often exceeds 90% in many low- and middle-income countries (LMICs). However, limited attention has been paid to patie...

    Authors: Vasco F. J. Cumbe, Alberto Gabriel Muanido, Morgan Turner, Isaias Ramiro, Kenneth Sherr, Bryan J. Weiner, Brian P. Flaherty, Monisha Sharma, Flávia Faduque, Ernesto Rodrigo Xerinda and Bradley H. Wagenaar
    Citation: Implementation Science 2022 17:37
    Content type: Study protocol Published on:
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Implementation Science

ISSN: 1748-5908