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  1. Access to essential medicines is core to saving lives and improving health outcomes of people worldwide, particularly in the low- and middle-income countries. Having a trained pharmacy workforce to manage the ...

    Authors: Solomon J Lubinga, Alisa M Jenny, Erin Larsen-Cooper, Jessica Crawford, Charles Matemba, Andy Stergachis and Joseph B Babigumira
    Citation: Implementation Science 2014 9:156
    Content type: Study protocol Published on:

  2. High-risk prescribing in primary care is common and causes considerable harm. Feedback interventions have small/moderate effects on clinical practice, but few trials explicitly compare different forms of feedb...

    Authors: Karen N Barnett, Marion Bennie, Shaun Treweek, Christopher Robertson, Dennis J Petrie, Lewis D Ritchie and Bruce Guthrie
    Citation: Implementation Science 2014 9:133
    Content type: Research Published on:

  3. This protocol builds on the development of a) a framework that identified the various supports (i.e. positions, activities, interventions) that a healthcare organisation or health system can implement for evid...

    Authors: Mathieu Ouimet, John N Lavis, Grégory Léon, Moriah E Ellen, Pierre-Olivier Bédard, Jeremy M Grimshaw and Marie-Pierre Gagnon
    Citation: Implementation Science 2014 9:146
    Content type: Study protocol Published on:

  5. Uganda changed its malaria treatment policy in response to evidence of resistance to commonly used antimalarials. The use of evidence in policy development—also referred to as knowledge translation (KT)—is cru...

    Authors: Juliet Nabyonga-Orem, Miriam Nanyunja, Bruno Marchal, Bart Criel and Freddie Ssengooba
    Citation: Implementation Science 2014 9:150
    Content type: Research Published on:

  6. In Denmark, guidelines on low back pain management are currently being implemented; in association with this, a clinical trial is conducted. A health economic evaluation is carried out alongside the clinical t...

    Authors: Cathrine Elgaard Jensen, Allan Riis, Kjeld Møller Pedersen, Martin Bach Jensen and Karin Dam Petersen
    Citation: Implementation Science 2014 9:140
    Content type: Study protocol Published on:

  7. The objectives of this paper are to describe the planned implementation and evaluation of the Building on Existing Tools to Improve Chronic Disease Prevention and Screening in Primary Care (BETTER 2) program w...

    Authors: Donna Patricia Manca, Kris Aubrey-Bassler, Kami Kandola, Carolina Aguilar, Denise Campbell-Scherer, Nicolette Sopcak, Mary Ann O'Brien, Christopher Meaney, Vee Faria, Julia Baxter, Rahim Moineddin, Ginetta Salvalaggio, Lee Green, Andrew Cave and Eva Grunfeld
    Citation: Implementation Science 2014 9:135
    Content type: Study protocol Published on:

  8. The aim of the study presented in this article is to analyse the determinants of telemedicine use. To that end, the study makes two basic contributions. First, it considers six working hypotheses in the contex...

    Authors: Francesc Saigí-Rubió, Joan Torrent-Sellens and Ana Jiménez-Zarco
    Citation: Implementation Science 2014 9:128
    Content type: Research Published on:

  9. One of the greatest challenges in healthcare is how to best translate research evidence into clinical practice, which includes how to change health-care professionals' behaviours. A commonly held view is that ...

    Authors: Janet E Squires, Katrina Sullivan, Martin P Eccles, Julia Worswick and Jeremy M Grimshaw
    Citation: Implementation Science 2014 9:152
    Content type: Systematic review Published on:

  10. Treatment of patients with multimorbidity is challenging. A rational reduction of long-term drugs can lead to decreased mortality, less acute hospital treatment, and a reduction of costs. Simplification of dru...

    Authors: Christin Löffler, Eva Drewelow, Susanne D Paschka, Martina Frankenstein, Julia Eger, Lisa Jatsch, Emil C Reisinger, Johannes F Hallauer, Bernd Drewelow, Karen Heidorn, Helmut Schröder, Anja Wollny, Gönther Kundt, Christian Schmidt and Attila Altiner
    Citation: Implementation Science 2014 9:151
    Content type: Study protocol Published on:

  11. Decision boxes (Dboxes) provide clinicians with research evidence about management options for medical questions that have no single best answer. Dboxes fulfil a need for rapid clinical training tools to prepa...

    Authors: Anik MC Giguere, Michel Labrecque, R Brian Haynes, Roland Grad, Pierre Pluye, France Légaré, Michel Cauchon, Matthew Greenway and Pierre-Hugues Carmichael
    Citation: Implementation Science 2014 9:144
    Content type: Research Published on:

  12. Combination antiretroviral therapy (cART) is the current strategy to prevent mother-to-child transmission (PMTCT) of HIV. Women initiated on cART should continue taking treatment life-long or stop after cessat...

    Authors: Lore Claessens, Anna Voce, Stephen Knight, Benn Sartorius and Ashraf Coovadia
    Citation: Implementation Science 2014 9:139
    Content type: Study protocol Published on:

  13. Delirium in critically ill patients has a strong adverse impact on prognosis. In spite of its recognized importance, however, delirium screening and treatment procedures are often not in accordance with curren...

    Authors: Erwin Ista, Zoran Trogrlic, Jan Bakker, Robert Jan Osse, Theo van Achterberg and Mathieu van der Jagt
    Citation: Implementation Science 2014 9:143
    Content type: Study protocol Published on:

  14. Clinicians' emotions about practice are a potentially powerful yet largely overlooked factor in implementation of good-quality care. The present paper expands the current, limited evidence about clinicians' em...

    Authors: Niina Kolehmainen and Jennifer McAnuff
    Citation: Implementation Science 2014 9:141
    Content type: Research Published on:

  15. Despite the availability of psychosocial evidence-based practices (EBPs), treatment and outcomes for persons with mental disorders remain suboptimal. Replicating Effective Programs (REP), an effective implemen...

    Authors: Amy M Kilbourne, Daniel Almirall, Daniel Eisenberg, Jeanette Waxmonsky, David E Goodrich, John C Fortney, JoAnn E Kirchner, Leif I Solberg, Deborah Main, Mark S Bauer, Julia Kyle, Susan A Murphy, Kristina M Nord and Marshall R Thomas
    Citation: Implementation Science 2014 9:132
    Content type: Study protocol Published on:

  17. Process evaluation is vital for understanding how interventions function in different settings, including if and why they have different effects or do not work at all. This is particularly important in trials ...

    Authors: Abby Haynes, Sue Brennan, Stacy Carter, Denise O'Connor, Carmen Huckel Schneider, Tari Turner and Gisselle Gallego
    Citation: Implementation Science 2014 9:113
    Content type: Study protocol Published on:

  18. The systematic involvement of project beneficiaries in community maternal and child health programmes remains low and limited, especially during the formative stages of the project cycle. Understanding how pos...

    Authors: Brynne Gilmore, Frédérique Vallières, Eilish McAuliffe, Nazarius Mbona Tumwesigye and Gilbert Muyambi
    Citation: Implementation Science 2014 9:137
    Content type: Research Published on:

  19. Knowledge translation (KT) supports use of evidence in healthcare decision making but is not widely practiced. Mentoring is a promising means of developing KT capacity. The purpose of this scoping systematic r...

    Authors: Anna R Gagliardi, Fiona Webster, Laure Perrier, Mary Bell and Sharon Straus
    Citation: Implementation Science 2014 9:122
    Content type: Research Published on:

  20. Osteoporosis affects over 200 million people worldwide at a high cost to healthcare systems, yet gaps in management still exist. In response, we developed a multi-component osteoporosis knowledge translation (...

    Authors: Monika Kastner, Anna M Sawka, Jemila Hamid, Maggie Chen, Kevin Thorpe, Mark Chignell, Joycelyne Ewusie, Christine Marquez, David Newton and Sharon E Straus
    Citation: Implementation Science 2014 9:109
    Content type: Research Published on:

  21. There are few studies describing how to scale up effective capacity-building approaches for public health practitioners. This study tested local-level evidence-based decision making (EBDM) capacity-building ef...

    Authors: Julie A Jacobs, Kathleen Duggan, Paul Erwin, Carson Smith, Elaine Borawski, Judy Compton, Luann D’Ambrosio, Scott H Frank, Susan Frazier-Kouassi, Peggy A Hannon, Jennifer Leeman, Avia Mainor and Ross C Brownson
    Citation: Implementation Science 2014 9:124
    Content type: Research Published on:

  22. There is a growing interest to study the transfer of evidence-based information into daily practice. The evidence-based programme Rehabilitation, Sports and Exercise (RSE) that aims to stimulate an active life...

    Authors: Femke Hoekstra, Roelina A Alingh, Cees P van der Schans, Florentina J Hettinga, Marjo Duijf, Rienk Dekker and Lucas HV van der Woude
    Citation: Implementation Science 2014 9:127
    Content type: Study protocol Published on:

  23. Finding current best evidence for clinical decisions remains challenging. With 3,000 new studies published every day, no single evidence-based resource provides all answers or is sufficiently updated. McMaster...

    Authors: Thomas Agoritsas, Emma Iserman, Nicholas Hobson, Natasha Cohen, Adam Cohen, Pavel S Roshanov, Miguel Perez, Chris Cotoi, Rick Parrish, Eleanor Pullenayegum, Nancy L Wilczynski, Alfonso Iorio and R Brian Haynes
    Citation: Implementation Science 2014 9:125
    Content type: Study protocol Published on:

  24. The implementation of innovations (i.e., new tools and practices) in healthcare organizations remains a significant challenge. The objective of this study was to examine the key interpersonal, organizational, and...

    Authors: Robin Urquhart, Geoffrey A Porter, Joan Sargeant, Lois Jackson and Eva Grunfeld
    Citation: Implementation Science 2014 9:121
    Content type: Research Published on:

  25. Despite great need, the number of HIV prevention implementation studies remains limited. The challenge for researchers, in this time of limited HIV services agency resources, is to conceptualize and test how t...

    Authors: Susan S Witte, Elwin Wu, Nabila El-Bassel, Timothy Hunt, Louisa Gilbert, Katie Potocnik Medina, Mingway Chang, Ryan Kelsey, Jessica Rowe and Robert Remien
    Citation: Implementation Science 2014 9:116
    Content type: Research Published on:

  26. The need to better understand processes of removing, reducing, or replacing healthcare services that are no longer deemed essential or effective is common across publicly funded healthcare systems. This paper ...

    Authors: Glenn Robert, Jenny Harlock and Iestyn Williams
    Citation: Implementation Science 2014 9:123
    Content type: Research Published on:

  27. Since 2007, the Mental Health Commission of Canada has worked collaboratively across all provinces to publish a framework and strategy for recovery and well-being. This federal document is now mandated as poli...

    Authors: Melissa M Park, Hiba Zafran, Janet Stewart, Jon Salsberg, Carolyn Ells, Suzanne Rouleau, Orly Estein and Thomas W Valente
    Citation: Implementation Science 2014 9:119
    Content type: Study protocol Published on:

  28. Despite the recognition of the importance of evidence-informed health policy and practice, there are still barriers to translating research findings into policy and practice. The present study aimed to establi...

    Authors: Rhona M Mijumbi, Andrew D Oxman, Ulysses Panisset and Nelson K Sewankambo
    Citation: Implementation Science 2014 9:114
    Content type: Research Published on:

  30. Like many new fields, implementation science has become vulnerable to instrumentation issues that potentially threaten the strength of the developing knowledge base. For instance, many implementation studies r...

    Authors: Ruben G Martinez, Cara C Lewis and Bryan J Weiner
    Citation: Implementation Science 2014 9:118
    Content type: Debate Published on:

  31. Most national and provincial commissions on healthcare services in Canada over the past decade have recommended that primary care services be strengthened in order to guarantee each citizen access to a family ...

    Authors: Mylaine Breton, Astrid Brousselle, Antoine Boivin, Christine Loignon, Nassera Touati, Carl-Ardy Dubois, Kareen Nour, Djamal Berbiche and Danièle Roberge
    Citation: Implementation Science 2014 9:117
    Content type: Study protocol Published on:

  32. Evidence from clinical practice and the extant literature suggests that post-operative pain assessment and treatment is often suboptimal. Poor pain management is likely to persist until pain management practic...

    Authors: Mari Botti, Bridie Kent, Tracey Bucknall, Maxine Duke, Megan-Jane Johnstone, Julie Considine, Bernice Redley, Susan Hunter, Richard de Steiger, Marlene Holcombe and Emma Cohen
    Citation: Implementation Science 2014 9:110
    Content type: Study protocol Published on:

  33. Depressive symptoms are highly prevalent in old age, but they remain mostly untreated. Several clinical trials have shown promising results in preventing or reducing depressive symptoms. However, it is not cle...

    Authors: Ilse MJ van Beljouw, Miranda GH Laurant, Marjolijn Heerings, Max L Stek, Harm WJ van Marwijk and Eric van Exel
    Citation: Implementation Science 2014 9:107
    Content type: Research Published on:

  34. Computerized clinical decision support systems (CDSSs) have been shown to improve the efficiency and quality of patient care by connecting healthcare professionals with high quality, evidence-based information...

    Authors: Lorenzo Moja, Elisa Giulia Liberati, Laura Galuppo, Mara Gorli, Marco Maraldi, Oriana Nanni, Giulio Rigon, Pietro Ruggieri, Francesca Ruggiero, Giuseppe Scaratti, Alberto Vaona and Koren Hyogene Kwag
    Citation: Implementation Science 2014 9:105
    Content type: Study protocol Published on:

  35. The need for high-quality evidence that is applicable in real-world, routine settings continues to increase. Pragmatic trials are designed to evaluate the effectiveness of interventions in real-world settings,...

    Authors: Bridget Gaglio, Siobhan M Phillips, Suzanne Heurtin-Roberts, Michael A Sanchez and Russell E Glasgow
    Citation: Implementation Science 2014 9:96
    Content type: Methodology Published on:

  36. There is as yet no evidence on the feasibility of implementing recommendations from the National Institute of Health and Care Excellence (NICE) osteoarthritis (OA) guidelines in primary care, or of the effect ...

    Authors: Krysia S Dziedzic, Emma L Healey, Mark Porcheret, Bie Nio Ong, Chris J Main, Kelvin P Jordan, Martyn Lewis, John J Edwards, Clare Jinks, Andrew Morden, Gretl A McHugh, Sarah Ryan, Andrew Finney, Sue Jowett, Raymond Oppong, Ebenezer Afolabi…
    Citation: Implementation Science 2014 9:95
    Content type: Study protocol Published on:

  37. The lack of high quality timely data for evidence-informed decision making at the district level presents a challenge to improving maternal and newborn survival in low income settings. To address this problem,...

    Authors: Tanya Marchant, Joanna Schellenberg, Stefan Peterson, Fatuma Manzi, Peter Waiswa, Claudia Hanson, Silas Temu, Kajjo Darious, Yovitha Sedekia, Joseph Akuze and Alexander K Rowe
    Citation: Implementation Science 2014 9:112
    Content type: Methodology Published on:

  38. The information contained in histopathology reports on surgical resections of cancer is fundamental for both patient treatment and cancer registries. Electronic synoptic histopathology reporting is considered ...

    Authors: Bettina Casati, Hans Kristian Haugland, Gunn Marit J Barstad and Roger Bjugn
    Citation: Implementation Science 2014 9:111
    Content type: Research Published on:

  39. Substance abuse is a worldwide public health concern. Extensive scientific research has shown that screening and brief interventions for substance use disorders administered in primary care provide substantial...

    Authors: Kathryn J Gill, Emily Campbell, Gail Gauthier, Spyridoula Xenocostas, Dara Charney and Ann C Macaulay
    Citation: Implementation Science 2014 9:108
    Content type: Study protocol Published on:

  40. Organizational culture is considered by policy-makers, clinicians, health service managers and researchers to be a crucial mediator in the success of implementing health service redesign. It is a challenge to ...

    Authors: Nicola K Gale, Jonathan Shapiro, Hugh S T McLeod, Sabi Redwood and Alistair Hewison
    Citation: Implementation Science 2014 9:106
    Content type: Methodology Published on:

  41. To facilitate translation of evidence into clinical practice, it is critical that clear, specific, and detailed information about interventions is provided in publications to promote replication, appropriate a...

    Authors: Jamie Bryant, Megan E Passey, Alix E Hall and Rob W Sanson-Fisher
    Citation: Implementation Science 2014 9:94
    Content type: Systematic review Published on:

  43. Evidence-based health promotion programs developed and tested in the general population typically exclude people with disabilities. To address this gap, a set of methods and criteria were created to adapt evid...

    Authors: James H Rimmer, Kerri A Vanderbom, Linda G Bandini, Charles E Drum, Karen Luken, Yolanda Suarez-Balcazar and Ian D Graham
    Citation: Implementation Science 2014 9:100
    Content type: Methodology Published on:

  44. Although evidence-based treatments are considered the gold standard for clinical practice, it is widely recognized that evidence-based treatment implementation in real world practice settings has been limited....

    Authors: Sarah B Hunter, Lynsay Ayer, Bing Han, Bryan R Garner and Susan H Godley
    Citation: Implementation Science 2014 9:104
    Content type: Study protocol Published on:

  45. The tailoring of implementation interventions includes the identification of the determinants of, or barriers to, healthcare practice. Different methods for identifying determinants have been used in implement...

    Authors: Jane Krause, Jan Van Lieshout, Rien Klomp, Elke Huntink, Eivind Aakhus, Signe Flottorp, Cornelia Jaeger, Jost Steinhaeuser, Maciek Godycki-Cwirko, Anna Kowalczyk, Shona Agarwal, Michel Wensing and Richard Baker
    Citation: Implementation Science 2014 9:102
    Content type: Research Published on:

  46. The Graded Repetitive Arm Supplementary Program (GRASP) is a hand and arm exercise programme designed to increase the intensity of exercise achieved in inpatient stroke rehabilitation. GRASP was shown to be ef...

    Authors: Louise A Connell, Naoimh E McMahon, Jocelyn E Harris, Caroline L Watkins and Janice J Eng
    Citation: Implementation Science 2014 9:90
    Content type: Research Published on:

  47. Clinical decision rules (CDRs) can be an effective tool for knowledge translation in emergency medicine, but their implementation is often a challenge. This study examined whether the Theory of Planned Behavio...

    Authors: Richard Perez, Jamie C Brehaut, Monica Taljaard, Ian G Stiell, Catherine M Clement and Jeremy Grimshaw
    Citation: Implementation Science 2014 9:88
    Content type: Research Published on:

  48. Evidence of the effectiveness of printed educational messages in narrowing the gap between guideline recommendations and practice is contradictory. Failure to screen for retinopathy exposes primary care patien...

    Authors: Merrick Zwarenstein, Susan K Shiller, Ruth Croxford, Jeremy M Grimshaw, Diane Kelsall, J Michael Paterson, Andreas Laupacis, Peter C Austin, Karen Tu, Lingsong Yun and Janet E Hux
    Citation: Implementation Science 2014 9:87
    Content type: Research Published on:

  49. Theory-based process evaluations conducted alongside randomized controlled trials provide the opportunity to investigate hypothesized mechanisms of action of interventions, helping to build a cumulative knowle...

    Authors: Jeremy M Grimshaw, Justin Presseau, Jacqueline Tetroe, Martin P Eccles, Jill J Francis, Gaston Godin, Ian D Graham, Janet E Hux, Marie Johnston, France Légaré, Louise Lemyre, Nicole Robinson and Merrick Zwarenstein
    Citation: Implementation Science 2014 9:86
    Content type: Research Published on:

  50. There has been a rapid increase in the publication of guidelines for managing obesity and weight gain during pregnancy over the past five years. Healthcare professionals have identified multiple barriers to th...

    Authors: Nicola Heslehurst, Lisa Crowe, Shannon Robalino, Falko F Sniehotta, Elaine McColl and Judith Rankin
    Citation: Implementation Science 2014 9:97
    Content type: Short report Published on:
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Implementation Science

ISSN: 1748-5908