Phase of care | EBP | Source | Definition | Include in final list | Measurable | Resource intensive | Source credibility | ||
---|---|---|---|---|---|---|---|---|---|
Yes | No | Maybe | M (SD) | M (SD) | M (SD) | ||||
1 | Lung-protective ventilation | Fan et al. (2017) [4] | Mechanical ventilation using lower tidal volumes (4–8 ml/kg predicted body weight) and lower inspiratory pressures (plateau pressure < 30 cm H2O) for adult patients with ARDS | 39 (97.5%) | 0 (0.0%) | 1 (2.5%) | 4.79 (0.47) | 3.02 (1.17) | 4.63 (0.66) |
1 | Prone positioning | Fan et al. (2017) [4] | Prone positioning for more than 12 h/day for adult patients with severe ARDS | 28 (75.7%) | 2 (5.4%) | 7 (18.9%) | 4.54 (0.68) | 4.08 (1.27) | 4.32 (0.78) |
2 | Analgesia-first approach to sedation | Strom (2010) [10] | Strategy to keep the amount and duration of sedation to a minimum | 25 (65.8%) | 4 (10.5%) | 9 (23.7%) | 3.53 (1.18) | 3.47 (1.16) | 3.89 (0.79) |
2 | Protocol-based pain assessment and management | Devlin et al. (2018) [11] | Routine use of an assessment-driven, protocol-based, stepwise approach for pain and sedation management in critically ill adults. Pain should be treated before a sedative agent is considered | 28 (73.7%) | 5 (13.2%) | 5 (13.2%) | 3.66 (1.24) | 3.42 (1.29) | 3.97 (0.87) |
2 | Conservative fluid management | Semler et al. (2016) [12] | Conservative fluid management. | 24 (61.5%) | 4 (10.3%) | 11 (28.2%) | 3.49 (1.19) | 3.26 (1.19) | 3.78 (0.85) |
2 | Daily awakening and breathing trials | Girard et al. (2008) [13] | Use of daily sedative interruption/nurse-protocolized sedation to achieve and maintain a light level of sedation | 32 (84.2%) | 0 (0.0%) | 6 (15.8%) | 4.13 (0.92) | 3.41 (1.16) | 4.35 (0.68) |
2 | Early mobilization | Devlin et al. (2018) [11] | For acutely hospitalized patients who have been mechanically ventilated for > 24 h, suggested protocolized rehabilitation directed toward early mobilization | 32 (82.1%) | 1 (2.6%) | 6 (15.4%) | 4.08 (0.84) | 4.21 (0.98) | 4.19 (0.70) |
2 | Sedation protocols | Devlin et al. (2018) [11] | Using either propofol or dexmedetomidine is preferred over benzodiazepines for sedation in critically ill, mechanically ventilated adults | 35 (89.7%) | 1 (2.6%) | 3 (7.7%) | 4.49 (0.79) | 3.13 (1.36) | 4.18 (0.93) |
3 | Ventilator liberation protocol | Schmidt et al. (2017) [14] | Manage acutely hospitalized adults who have been MV > 24 h with a ventilator liberation protocol (designed to reduce variation in practice) | 25 (65.8%) | 3 (7.9%) | 10 (26.3%) | 4.03 (1.03) | 3.58 (1.18) | 4.15 (0.93) |
3 | Extubation to preventive noninvasive ventilation | Ouellette et al. (2017) [15] | Extubation to preventive noninvasive ventilation (NIV) | 11 (29.0%) | 16 (42.1%) | 11 (29.0%) | 3.80 (1.01) | 3.72 (1.03) | 3.60 (0.95) |
3 | Extubation to high-flow nasal cannula | Hernandez (2016) [16] | Extubation to high-flow nasal cannula | 10 (27.0%) | 11 (29.7%) | 16 (43.2%) | 4.00 (0.82) | 3.46 (1.04) | 3.50 (0.93) |