|Topic||Questions from an entrepreneurial perspective|
|Problem or condition||
What medical or public health or social problem does your innovation address?|
How many people are afflicted with problem?
How great is the public health burden or health burden of the condition your innovation addresses?
|The innovation (new treatment, diagnostic procedure, protocol, device)||
How ready is your innovation for adoption in the real world? What is its readiness for adoption?|
How strong is the empirical evidence supporting its effectiveness?
How many people could benefit from your innovation?|
How soon would the benefit be realized?
What is the reduction in adverse outcomes from your innovation?
Who would use your innovation (who would put it into practice)?|
Who or what is the adopter group? (individual providers? Hospitals? Health systems? Patients? Communities?
|Market opportunity, size, and demand||
What indication do you have that your innovation is wanted?|
Who wants it? What is the scale and level of demand?
Do other solutions to this problem exist, and how does your innovation compare to other available solutions?|
What are the barriers or challenges to the adoption of your innovation?
|How viable is the innovation in the adopter market?||
Is the product you want to implement what the market is willing to pay for?|
How much will your innovation cost to develop, deliver, and market to users? (Cost)
Who would pay, and why? (payer)
What is the “invest-ability” threshold? (input/return)|
What is the internal rate of return (IRR) potential and potential % reduction in adverse outcomes attributable to your innovation?
What will make the innovation sustainable over time?
Who is the initial target audience?|
How much market share can you capture?