Table 1 Clinical Indicators targeted by the intervention package

Risky prescribing

Proportion of patients meeting at least one of nine indicators of high-risk NSAID and anti-platelet prescribing:

prescription of a traditional oral NSAID or low-dose aspirin in patients with a history of peptic ulceration without co-prescription of gastro-protection;

traditional oral NSAID in patients aged 75 years or over without co-prescription of gastro-protection;

traditional oral NSAID and aspirin in patients aged 65 years or over without co-prescription of gastro-protection;

aspirin and clopidogrel in patients aged 65 years or over without co-prescription of gastro-protection;

warfarin and traditional oral NSAID;

warfarin and low-dose aspirin or clopidogrel without co-prescription of gastro-protection;

oral NSAID in patients with heart failure;

oral NSAID in patients prescribed both a diuretic and an angiotensin-converting-enzyme inhibitor (ACE-I) or angiotensin receptor blocker (ARB);

oral NSAID in patients with chronic kidney disease (CKD).

Diabetes

Proportion of patients with type 2 diabetes achieving all three treatment targets:

BP below 140/80 mmHg (or 130/80 mmHg if kidney, eye or cerebrovascular damage);

HbA1c value below or equal to 59 mmol/mol;

cholesterol level below or equal to 5.0 mmol/l

Blood pressure

Proportion of patients achieving the lowest appropriate BP target:

under 140/90 mmHg if aged under 80 years with hypertension, coronary heart disease, peripheral arterial disease, a history of stroke or transient ischemic attack, or a 10 year cardiovascular disease risk of 20% or higher;

under 150/90 mmHg if aged 80 years and over with hypertension;

under 140/80 mmHg if aged under 80 years with diabetes, under 130/80 mmHg if complications of diabetes or aged under 80 years with chronic kidney disease and proteinuria.

Anticoagulation

Combined proportion of men with AF and a CHA2DS2-VASc score of 1 and women with a CHA2DS2-VASc score of 2 or above prescribed anticoagulation therapy.