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From: Assessment of the quality of recommendations from 161 clinical practice guidelines using the Appraisal of Guidelines for Research and Evaluation–Recommendations Excellence (AGREE-REX) instrument shows there is room for improvement

AGREE-REX domains and items
Domains Items
1. Evidence justification 1. Evidence
2. Clinical applicability justification 2. Clinical relevance
3. Relevance to patients/populations
4. Implementation relevance
3. Values justification 5. Guideline developer values
6. Target user values
7. Patient population values
8. Policy values
9. Alignment of values
4. Feasibility considerations 10. Local applicability
11. Resources, capacity, and tools