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Table 1 Outcome measures by RE-AIM category

From: The Balanced Opioid Initiative: protocol for a clustered, sequential, multiple-assignment randomized trial to construct an adaptive implementation strategy to improve guideline-concordant opioid prescribing in primary care

Domain

Source

Months* collected

Reach: # and % of patients excluded vs. participating (incl. characteristics)

EHR

1–21

Effectiveness: prescriber averages of MME dose per day per opioid patient over the past 3 months (primary outcome)

EHR

1–21

# and % of patients completing urine drug testing (past 12 months)

EHR

1–21

# and % of patients screened for mental health using PHQ-2 (past 12 months)

EHR

1–21

Mental health (PHQ-9) scores for patients screening positive on PHQ-2 (past 12 months)

EHR

1–21

Overall rate and dose of opioid-benzodiazepine co-prescribing

EHR

1–21

# and % of patients with treatment agreements (past 12 months)

EHR

1–21

# and % of opioid prescriptions above 90 MME

EHR

1–21

Patient attendance at scheduled clinic visits

EHR

1–21

# and % of patients prescribed buprenorphine

EHR

1–21

# and % of patients with PEG-3 score (past 12 months)

EHR

1–21

PEG-3 scores (past 12 months)

EHR

1–21

Adoption (setting): # and % of participating clinics vs. all clinics (incl. characteristics)

Health system

1–21

Adoption (staff): # and % of participating staff vs. all eligible clinic staff (incl. characteristics)

Clinic

1–21

Clinician attendance at intervention meetings

Research team

1–21

Implementation: Hours of intervention received per clinic and prescriber

Research team

1–21

Adaptations made to protocols during intervention period

Research team

1–21

Assessment of moderators: clinic-level experience in QI, size of clinic (# patients), # and % of patients at the clinic on opioid doses > 90 MME

Research team, EHR

0, 3, 9, 21

Qualitative assessment of mechanisms of action and factors influencing implementation

Research team

1–21

Cost of each implementation sequence and combination

Research team

1–21

Maintenance: 6-month follow-up on all effectiveness outcomes

EHR

22–27

  1. EHR electronic health record
  2. *Months correspond to intervention months