Table 1 Alignment of study activities with Medical Research Council UK measures of intervention complexity

Number of interacting components within the experimental and control interventions

Activities include:

 • Education and training

 • Continuous quality improvement workshops

 • Provision of medication

There is a retrospective control period and a prospective experimental period.

Number and difficulty of behaviors required by those delivering or receiving the intervention

Health care providers need to significantly change practice to start doing contact investigation, which was not previously undertaken:

 • Details of contacts need to be documented on a new TB form.

 • Contacts need to be seen by healthcare providers, assessed, investigated appropriately, commenced on medication as appropriate, and followed up for at least 6 months.

 • Patients need to adhere to medication and medical follow-up appointments.

Number of groups or organizational levels targeted by the intervention

Five healthcare facilities (phase 1 implementation)

Seven healthcare facilities (phase 2 implementation)

District TB Program

District Health Authority

Number and variability of outcomes

There are six main outcomes:

Primary:

 • Number of individuals completing isoniazid preventive therapy (IPT).

Secondary (numbers and proportions of):

 • Index cases for whom contact investigation and management is undertaken

  ◦ All

  ◦ Smear-positive

  ◦ Smear-negative

 • Contacts reached for symptom screening

 • Contacts found to have active TB

 • Contacts eligible for IPT

 • Contacts commencing IPT.

Degree of flexibility or tailoring of the intervention permitted

A degree of tailoring is permitted since healthcare facilities differ (hospitals, primary care sites, rural, urban, etc.)