Skip to main content

Table 7 Summary of impact of academic detailing visits on secondary outcomes

From: The implementation of academic detailing and its effectiveness on appropriate prescribing of pain relief medication: a real-world cluster randomized trial in Belgian general practices

  ITT1 ITT2 PPR
  Step change [95% Wald CI]
Average defined daily dose of analgesic and NSAIDs per patient reimbursed for an analgesic or NSAID per month, in intervention compared to control group (SO1) 0.0640 [− 0.1916; 0.3196] 0.1090 [− 0.1484; 0.3664] 0.2186 [− 0.0707; 0.5079]
Odds of being reimbursed for paracetamol, in intervention compared to control group (SO2) 1.0081 [0.9932;1.0232] 0.9976 [0.9811; 1.0144] 1.0289 [0.9941; 1.0649]
Odds of being reimbursed for an NSAID, in intervention compared to control group (SO3) 1.0078 [0.9943; 1.0214] 1.0055 [0.9918; 1.0194] 1.0269* [1.0033; 1.0510]
Odds of being reimbursed for both an NSAID and a PPI when reimbursed for an NSAID for the first time in 3 months, in intervention compared to control group (SO4) 1.0423 [0.9689; 1.1212] 1.0482 [0.9621; 1.1420] 1.0155 [0.9532; 1.0819]
  Change in trend [95% Wald CI]
Average defined daily dose of analgesic and NSAIDs per patient reimbursed for an analgesic or NSAID per month, in intervention compared to control group (SO1) 0.0455 [− 0.0183; 0.1094] 0.0316 [− 0.0369; 0.1001] 0.0374 [− 0.0470; 0.1218]
Odds of being reimbursed for paracetamol, in intervention compared to control group (SO2) 0.9867* [0.9766; 0.9968] 0.9889* [0.9785; 0.9994] 0.9960 [0.9871; 1.0049]
Odds of being reimbursed for an NSAID, in intervention compared to control group (SO3) 0.9907 [0.9801; 1.0015] 0.9907 [0.9809; 1.0006] 0.9998 [0.9925; 1.0072]
Odds of being reimbursed for both an NSAID and a PPI when reimbursed for an NSAID for the first time in 3 months, in intervention compared to control group (SO4) 0.9907 [0.9539; 1.0289] 0.9972 [0.9564; 1.0398] 1.0037 [0.9542; 1.0557]
  1. Step change difference before and after the intervention; change in trend monthly change after the intervention; CI confidence interval; NSAID nonsteroidal anti-inflammatory drug; PPI proton pump inhibitor; ITT1 adjusted intention to treat analysis after dropping contaminated controls; ITT2 adjusted intention to treat analysis after dropping contaminated controls and fully contaminated cases; PPR per protocol analysis; *p value < 0.05