Skip to main content

Table 4 SPPiRE PIP, miscellaneous

From: Supporting prescribing in older people with multimorbidity and significant polypharmacy in primary care (SPPiRE): a cluster randomised controlled trial protocol and pilot

Drug group

PIP

Reason

Methotrexate

Not prescribed as weekly [33]

Increased risk of potentially fatal medication errors

Prescribed >1 strength tablet [33]

Opioids

Used regularly with no laxative [15]

Risk of severe constipation

Corticosteroids

Used ≥12 weeks with no bone protection [15]

Risk of fracture

PPI

For uncomplicated PUD/erosive peptic oesophagitis at full therapeutic dose ≥8 weeks [15]

Not indicated

Metformin

With eGFR <30 ml/min/ 1.73m2 [15]

Risk of lactic acidosis

  1. Abbreviations: eGFR estimated glomerular filtration rate, PUD peptic ulcer disease
Back to article page

Implementation Science

ISSN: 1748-5908