Table 1 Examples of reminders generated by MediDSS from the EBMeDS and SFINX databases

Clinical reminders in MediDSS based on EBMeDS database

Drug-drug interaction reminders in MediDSS based on SFINX database [66]

Adjusting warfarin dose in atrial fibrillation: If a patient with atrial fibrillation and warfarin treatment, who has not had heart valve replacement, has not had an INR test during the last 8 weeks, the text “Last INR over 8 weeks ago, order INR?” is shown.

Interaction between spironolactone and potassium: “The combination of potassium supplements and potassium sparing diuretics can result in hyperkalemia.”

If a new INR result is outside the range 1.9–3.2, the text “Check warfarin dose (INR target 2.0–3.0, but note that if the patient has a mechanical mitral valve, the INR target is 2.5–3.5)” is shown, with link to dose calculator.

Interaction between warfarin and acetylsalicylic acid: “Concomitant use is associated with an increased risk of bleeding.”