An effectiveness-implementation hybrid trial study protocol targeting posttraumatic stress disorder and comorbidity

Table 4 Stepped wedge power for TSOS outcomes

Continuous outcomes	PTSD Checklist	PHQ-9	AUDIT	MOS SF-PCS
Cluster size at baseline	40	40	40	40
Cluster size estimation at 12-month (25 % attrition)	30	30	30	30
Total number of clusters	24	24	24	24
Alpha	0.05	0.05	0.05	0.05
Power	0.8	0.8	0.8	0.8
ICC	0.02	0.0259	0.02	0.02
Baseline mean (SD)	50 (15)	14 (6)	10 (5)	50 (10)
Autocorrelation	0.7	0.7	0.7	0.7
Follow-up time points (including baseline)	4	4	4	4
Minimal detectable effect size	0.23	0.23	0.23	0.23

PTSD posttraumatic stress disorder, PTSD Checklist Civilian Version [58], PHQ-9 Patient Health Questionnaire [82], AUDIT Alcohol Use Disorders Identification Test [85], MOS SF PCS Medical Outcomes Study Short Form Physical Components Summary Score [126], ICC intraclass correlation, SD standard deviation

ISSN: 1748-5908