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Table 4 Primary and secondary continuous outcomes reported by GPs and patients

From: A tailored intervention to implement guideline recommendations for elderly patients with depression in primary care: a pragmatic cluster randomised trial

  Intervention Control Estimated differencea between intervention and control group (%) (lower CL (%), upper CL (%))
N Mean (%) (SD (%)) N Mean (%) (SD (%))
Primary outcome
Mean adherence 51 58 (20) 73 53 (18) 2 (−11, 7)
Secondary outcome
GP assessed CGI-Ib 141 2.58 (1.04) 170 2.55 (1.04) 0.046 (−0.29, 0.38)
Patient assessed PGIb 55 2.20 (1.37) 69 2.10 (1.36) 0.18 (−0.47, 0.83)
HADS depression 60 6.55 (4.74) 70 6.83 (4.17) −0.55 (−2.70, 1.60)
HADS anxiety 58 8.09 (4.86) 69 8.49 (4.11) −0.075 (−2.01, 2.16)
HADS total 58 14.62 (9.01) 68 15.12 (7.64) −0.38 (−4.27, 3.51)
Lonelinessc 60 1.58 (1.11) 74 1.65 (1.00) 0.34 (−0.97, 0.30)
Sleeping problems improvedb 31 2.32 (1.01) 43 2.05 (1.11) 0.57 (−0.06, 1.20)
Ability to cope with anxiety improvedb 38 2.45 (1.16) 40 2.07 (1.39) 0.28 (−0.29, 0.91)
Problem solvingb 53 2.79 (1.22) 68 2.54 (1.30) 0.28 (−0.34, 0.91)
  1. aEstimated difference from final multivariate mixed model adjusting for size of municipality, proportion 80+ inhabitants in municipality, and potential effect modifiers with p value <0.3 in univariate analyses
  2. bMid-point 3, Likert-scale range 0-6, improvement indicated by lower than 3
  3. cBetter indicated by lower, range 0–3
  4. CGI-I clinical global impression scale improvement, CL confidence level, GP general practitioner, HADS hospital and anxiety scale, PGI patient global impression