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Table 4 Primary and secondary continuous outcomes reported by GPs and patients

From: A tailored intervention to implement guideline recommendations for elderly patients with depression in primary care: a pragmatic cluster randomised trial

 

Intervention

Control

Estimated differencea between intervention and control group (%) (lower CL (%), upper CL (%))

N

Mean (%) (SD (%))

N

Mean (%) (SD (%))

Primary outcome

Mean adherence

51

58 (20)

73

53 (18)

2 (−11, 7)

Secondary outcome

GP assessed CGI-Ib

141

2.58 (1.04)

170

2.55 (1.04)

0.046 (−0.29, 0.38)

Patient assessed PGIb

55

2.20 (1.37)

69

2.10 (1.36)

0.18 (−0.47, 0.83)

HADS depression

60

6.55 (4.74)

70

6.83 (4.17)

−0.55 (−2.70, 1.60)

HADS anxiety

58

8.09 (4.86)

69

8.49 (4.11)

−0.075 (−2.01, 2.16)

HADS total

58

14.62 (9.01)

68

15.12 (7.64)

−0.38 (−4.27, 3.51)

Lonelinessc

60

1.58 (1.11)

74

1.65 (1.00)

0.34 (−0.97, 0.30)

Sleeping problems improvedb

31

2.32 (1.01)

43

2.05 (1.11)

0.57 (−0.06, 1.20)

Ability to cope with anxiety improvedb

38

2.45 (1.16)

40

2.07 (1.39)

0.28 (−0.29, 0.91)

Problem solvingb

53

2.79 (1.22)

68

2.54 (1.30)

0.28 (−0.34, 0.91)

  1. aEstimated difference from final multivariate mixed model adjusting for size of municipality, proportion 80+ inhabitants in municipality, and potential effect modifiers with p value <0.3 in univariate analyses
  2. bMid-point 3, Likert-scale range 0-6, improvement indicated by lower than 3
  3. cBetter indicated by lower, range 0–3
  4. CGI-I clinical global impression scale improvement, CL confidence level, GP general practitioner, HADS hospital and anxiety scale, PGI patient global impression
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Implementation Science

ISSN: 1748-5908