Table 2 Example calculation for determining number of patients classified as TP/TN/FP/FN per 1,000 based on pre-test probability of 20% (based on population with 20% prevalence of CMA in target population)
Reference standard | ||||
|---|---|---|---|---|
Disease present | Disease absent | |||
New Test | Positive | TP = sensitivity × 200 | FP = (1 - specificity) × 800 | |
Negative | FN = (1 - sensitivity) × 200 | TN = specificity × 800 | ||
Prevalence: 20% | 200 | 800 | 1000 | |