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Table 2 Bivariate associations with blood pressure medication intensification among 387 patients presenting with uncontrolled blood pressure

From: Multiple uncontrolled conditions and blood pressure medication intensification: an observational study

  BP medication intensification rates Odds ratio 95% Confidence Interval  
Patient Factors # intensified/total # %   lower limit upper limit P
Age (years)       
< 55 28/92 30.4 0.61 0.35 1.06 0.29
55 to 64 57/136 41.9 Referent   
≥ 65 50/159 31.5 0.64 0.39 1.03 0.36
Sex       
Male 133/373 35.7 Referent    
Female 2/14 14.3 0.3 0.07 1.36 0.12
Systolic BP (mmHg) (mean)       
< 140 21/122 17.2 Referent    
140 to 159 72/196 36.7 2.79 1.61 4.85 0.93
≥ 160 42/69 60.9 7.48 3.81 14.68 < 0.001
Systolic BP < 10 mmHg above goal       
Yes 39/203 19.2 Referent    
No 96/184 52.2 4.59 2.92 7.22 < 0.01
Number of medications*       
0 39/122 31.5 0.68 0.35 1.33 0.35
1 to 2 40/114 29.5 Referent    
3 to 4 34/97 25.1 0.79 0.40 1.53 0.89
5+ 22/54 13.9 0.79 0.40 1.56 0.89
Diabetes       
Present-Uncontrolled 36/98 36.7 1.37 0.76 2.49 0.52
Present-Controlled** 30/101 29.7 Referent    
Not present 69/188 36.7 1.37 0.82 2.30 0.46
Hyperlipidemia       
Present-Uncontrolled 33/103 32.0 1.46 0.87 2.45 0.11
Present-Controlled** 65/196 33.2 Referent    
Not present 37/88 42.1 0.95 0.57 1.58 0.33
Clinical scenario: Uncontrolled BP AND       
No diagnosed diabetes or HLD† 30/76 39.5 1.53 0.86 2.71 0.72
Controlled diabetes and/or HLD 47/157 29.9 Referent    
Either uncontrolled diabetes or HLD 43/122 35.3 1.27 0.77 2.11 0.56
Both uncontrolled diabetes and HLD 15/32 46.9 2.07 0.95 4.48 0.18
  1. *Medications for hypertension, diabetes, and/or hyperlipidemia prescribed in the 90 days prior to the index visit; **Includes missing laboratory data: 23 hemoglobin A1c levels and 41 lipid levels; †HLD = Hyperlipidemia