Assessing the impact of public funding in alleviating participant reduction and improving the retention rate in methadone maintenance treatment clinics in Taiwan: an interrupted time series analysis

Table 2 The impact of PMES policy intervention on the monthly average number of daily participants before (non-PMES period) and after the implementation of PMES (PMES period), divided into PMES only (2019/01~2019/12) and PMES with add-on MCAM later (2019/01~2019/08) in Taiwan

Model parameters	PMES only				PMES + add-on MCAM later
Model parameters	n	β	S.E.^a	P value	n	β	S.E.^a	P value
Overall	32				34
Intercept		128.58	4.78	< 0.01^*		101.31	4.39	< 0.01^*
Baseline slope		− 0.59	0.10	< 0.01^*		− 0.45	0.09	< 0.01^*
Level change after intervention		6.90	3.38	0.04^*		4.51	3.01	0.14
Slope change after intervention		0.62	0.12	< 0.01^*		0.29	0.10	< 0.01^*
Tiny	19				13
Intercept		40.35	1.13	< 0.01^*		51.18	1.21	< 0.01^*
Baseline slope		− 0.23	0.03	< 0.01^*		− 0.24	0.03	< 0.01^*
Level change after intervention		2.75	1.09	0.01^*		1.02	1.03	0.32
Slope change after intervention		0.47	0.05	< 0.01^*		0.62	0.04	< 0.01^*
Small	10				14
Intercept		110.55	6.11	< 0.01^*		113.16	5.97	< 0.01^*
Baseline slope		− 0.55	0.13	< 0.01^*		− 0.59	0.13	< 0.01^*
Level change after intervention		9.77	4.34	0.03^*		10.53	4.50	0.02^*
Slope change after intervention		0.50	0.16	< 0.01^*		0.45	0.16	< 0.01^*
Medium	3				7
Intercept		174.80	6.83	< 0.01^*		170.69	7.29	< 0.01^*
Baseline slope		− 0.61	0.14	< 0.01^*		− 0.55	0.15	< 0.01^*
Level change after intervention		1.55	4.28	0.72		−1.04	4.29	0.81
Slope change after intervention		0.15	0.14	0.29		− 0.64	0.15	< 0.01^*
Large	9				–
Intercept		438.99	12.27	< 0.01^*		–	–	–
Baseline slope		− 1.98	0.26	< 0.01^*		–	–	–
Level change after intervention		19.97	8.51	0.02^*		–	–	–
Slope change after intervention		1.97	0.32	< 0.01^*		–	–	–

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