Reporting of costs and economic impacts in randomized trials of de-implementation interventions for low-value care: a systematic scoping review

Falkenbach, Petra; Raudasoja, Aleksi J.; Vernooij, Robin W. M.; Mustonen, Jussi M. J.; Agarwal, Arnav; Aoki, Yoshitaka; Blanker, Marco H.; Cartwright, Rufus; Garcia-Perdomo, Herney A.; Kilpeläinen, Tuomas P.; Lainiala, Olli; Lamberg, Tiina; Nevalainen, Olli P. O.; Raittio, Eero; Richard, Patrick O.; Violette, Philippe D.; Tikkinen, Kari A. O.; Sipilä, Raija; Turpeinen, Miia; Komulainen, Jorma

doi:10.1186/s13012-023-01290-3

Implementation Science

Table 5 De-implementation impact on health care costs in studies, not specifying to whom change was allocated

From: Reporting of costs and economic impacts in randomized trials of de-implementation interventions for low-value care: a systematic scoping review

Author + year	Target clinical intervention	Direction of impact	Size of impact	Size in US $ (2021 value)
Alexander et al. (1996) [35]	Rehabilitation	Decreased	US $319,000/101 patient	516,000/101 patient^b
Avorn et al. (1983) [46]	Drug treatment	Decreased	US $19,740/year	45,800/year^b
Chazan et al. (2007) [62]	Drug treatment, AB	Decreased	US $186/4-month season/patient	238/4-month season/patient^b
Dormuth et al. (2012) [37]	Drug treatment	Decreased	US $465,000/2 years	550,000/2 years^b
Meeker et al. (2014) [63]	Drug treatment, AB	Decreased	US $70.4 million/annual/country (USA)	80.4 million/annual/country (USA)^b
Nejad et al. (2016) [44]	Drug treatment	Decreased	US $2000/3 months	2240/3 months^b
Ray et al. (2001) [64]	Drug treatment	Unchanged	US $331/patient	491/patient^b
Ilett et al. (2000) [65]	Drug treatment, AB	Decreased	16,130 AUD/3 months/56 GPs	21,815/3 months/56 GPs^d
Zwar et al. (1999) [27]	Drug treatment, AB	Decreased	273 AUD/doctor	378/doctor $^d
Butler et al. (2012) [26]	Drug treatment, AB	Decreased	830 GBP/year/practice	1410/year/practice^a
Gulliford et al. (2019) [38]	Drug treatment, AB	Unchanged	51-GBP annual cost/patient	71.4/annual cost/patient^a
Coenen et al. (2004) [42]	Drug treatment, AB	Decreased	7 EUR/patient	12.6/patient^c
Danaher et al. (2009) [66]	Drug treatment, AB	Unchanged	58.67 EUR	127.4^c
Le Corvoisier et al. (2013) [67]	Drug treatment, AB	Decreased	706 EUR	1073^c
Masia et al. (2009) [68]	Drug treatment, AB	Unchanged	18 EUR/patient	31.26/patient^c
Bernal-Delgado et al. (2002) [69]	Drug treatment	Unchanged	NA
Cummings et al. (1982) [70]	Diagnostic imaging, laboratory tests	Decreased	NA
Hamilton et al. (2007) [71]	Drug treatment	Unchanged	NA
Naughton et al. (2009) [29]	Drug treatment, AB	Unchanged	NA
Pagaiya et al. (2005) [72]	Drug treatment, AB and others	Decreased	NA
Pinto et al. (2018) [73]	Drug treatment	Unchanged	NA
Ruangkanchanasetr et al. (1993) [74]	Laboratory tests	Unchanged	NA
Smith et al. (2016) [75]	Drug treatment, AB	Unchanged	NA
Tang et al. (2016) [76]	Drug treatment, AB and injections	Decreased	NA
Wei et al. (2019) [77]	Drug treatment, AB	Unchanged	NA
Yang et al. (2014) [78]	Drug treatment, AB	Unchanged	NA

References of currency conversions
^aLawrence H. Officer and Samuel H. Williamson, “Computing ‘Real Value’ Over Time With a Conversion Between U.K. Pounds and U.S. Dollars, 1791 to Present,” Measuring Worth, 2022, www.measuringworth.com/exchange/
^bSamuel H. Williamson, “Seven Ways to Compute the Relative Value of a U.S. Dollar Amount, 1790 to present,” Measuring Worth, 2022. https://www.measuringworth.com/calculators/uscompare/
^cfirst converted with Lawrence H. Officer, "Exchange Rates Between the United States Dollar and Forty-one Currencies,", MeasuringWorth, 2022, http://www.measuringworth.com/exchangeglobal/ to usD, then with reference b to present value
^dFirst converted with Diane Hutchinson and Florian Ploeckl, “Five Ways to Compute the Relative Value of Australian Amounts, 1828 to the Present,” Measuring Worth, 2022, https://www.measuringworth.com/calculators/australiacompare/ and then with Lawrence H. Officer, “Exchange Rates Between the United States Dollar and Forty-one Currencies,” MeasuringWorth, 2022, http://www.measuringworth.com/exchangeglobal/. All conversions have been made on 25th October 2022

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ISSN: 1748-5908

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