Table 1 Summary of guideline recommendations for medications post-STEMI

Anti-platelets

Aspirin therapy (75-162 mg/day) indefinitely post-STEMI.

I A

P2Y₁₂-receptor inhibitor (clopidogrel, prasugrel, or ticagrelor) in combination with aspirin in patients post ACS

I A

P2Y₁₂-receptor inhibitor continued for at least 12 months if ACS managed with PCI and stent placement

I A

Statins

Statin therapy indefinitely for all patients with a prior cardiovascular event.

I A

Angiotensin-system agent

ACE inhibitor (or ARB if intolerant) post-STEMI indefinitely for all patients with left ventricular ejection fraction <40% and in those with hypertension, diabetes, or chronic kidney disease

I A

ACE inhibitor (or ARB) for all patients post-STEMI

IIa B

Beta-blockers

Beta-blockers for all patients post-STEMI

I A

Beta-blockers continued for at least three years post-STEMI

I B