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Table 2 Effective sample size, assuming different magnitudes of intracluster correlation (ICC)^

From: Fever, hyperglycaemia and swallowing dysfunction management in acute stroke: A cluster randomised controlled trial of knowledge transfer

ICC

Design Effect

Number of patients per group

Total number of patients required

0

1

280

560

0.01

1.4

400

800

0.015

1.85

520

1040

0.02

2.6

730

1460

0.03

4.4

1230

2460

  1. ^ 80% power at alpha = 0.05; nine ACU's per group; adjusted for loss to follow-up of 10%