Table 2 Patient population and primary outcome for each of 3 replicates
Replicate | Evidence/Practice Gap | Patients studied | Expected patient N | Primary Outcome |
|---|---|---|---|---|
1 | Use of ACE inhibitors, blood pressure and cholesterol-reducing drugs (ABCs); each fall short of guideline targets by at least 30% | All prevalent cases of persons with diabetes, aged ≥ 65 years | 280,000 | % of target patients receiving an ACE inhibitor, % receiving 2 or more antihypertensive, and % receiving lipid-lowering drug |
2 | Retinopathy screening in incident Type 2 DM; 50% below guideline-recommended levels | All incident cases of persons with diabetes, aged >30 years | 100,000 | % of target patients receiving complete eye exam from optometrist or ophthalmologist |
3 | Use of hydrochlorothiazide (HCTZ) as initial therapy in uncomplicated hypertension; ~40% below guideline-recommended levels | All patients ≥ 65 years, newly initiated on antihypertensive therapy | 30,000 | % of target patients receiving a diuretic |