Effect of core versus enhanced implementation strategies on adherence to a clinical pathway for managing anxiety and depression in cancer patients in routine care: a cluster randomised controlled trial

Table 6 Results with adherence as a binary outcome

Variable	Odds ratio (average difference to referent)	95% Confidence interval	p value	Adjusted means (%)^b
Implementation arm			0.35
Core	Referent			64.06
Enhanced	1.16	0.85–1.59		66.19
Step allocation^a			< 0.001
1	Referent			83.83
2	0.05	0.03–0.09		20.70
3	0.05	0.03–0.09		21.13
4	0.05	0.02–0.10		20.32

Note: As the interaction between implementation arm and step allocation was non-significant (p > 0.05), this table only presents the results of the main effects
^aStep 1 = minimal anxiety/depression, Step 2 = mild anxiety/depression, Step 3 = moderate anxiety/depression, Step 4 = severe anxiety/depression, Step 5 = very severe anxiety/depression but no patients scored in this Step
^b Adjusted mean differences in percentage of screening events achieving adherence (> 70%). Means have been adjusted for persons (due to repeated screens) and site (due to cluster randomisation)

ISSN: 1748-5908