Study protocol for a factorial-randomized controlled trial evaluating the implementation, costs, effectiveness, and sustainment of digital therapeutics for substance use disorder in primary care (DIGITS Trial)

Table 2 Random assignment of primary care clinics to two implementation strategies resulting in four implementation approaches (2x2 factorial design)

Implementation Strategy	Approach 1: Standard Implementation Only	Approach 2: Standard Implementation + Practice Facilitation	Approach 3: Standard Implementation + Health Coach	Approach 4 Standard Implementation + Both
Standard Implementation	YES	YES	YES	YES
Practice Facilitation	NO	YES	NO	YES
Health Coach	NO	NO	YES	YES

ISSN: 1748-5908