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Table 3 Results of the controlled interrupted time series analysis of opioid prescribing rates adjusted for gabapentinoid prescribing in Scotland

From: Assessing the impact of a national clinical guideline for the management of chronic pain on opioid prescribing rates: a controlled interrupted time series analysis

 

Estimate (95% confidence interval)

Standard error

P value

Difference in intercept, β4

220.83 (215.85, 225.81)

2.51

<0.01

Difference in pre-intervention trend, β5

1.31 (1.07, 1.54)

0.12

<0.01

Difference in change in level, β6

−9.09 (−16.69, −1.49)

3.84

0.02

Difference in change in trend, β7

−3.09 (−3.54, −2.64)

0.23

<0.01

Difference in post-intervention trend, β5+7

−1.78 (−2.13, −1.43)

0.17

<0.01

Adjusted relative change, %a

−24.85 (−28.13, −21.61)

n/a

n/a

Durbin-Watson statistic

1.53

n/a

n/a

  1. β4–7 are coefficients from the controlled interrupted time series analysis model; the intercept represents the outcome at the start of the study period; the relative change is calculated compared to the predicted value at the same time point had the pre-intervention trend continued
  2. aCalculated at quarter 2 2020. 95% confidence interval calculated using model bootstrapping