Table 7 Seven adaptation components cluster model. Clusters shown in Table 6 can be roughly summarized as the following: Cluster 1: Unplanned program content changes for a variety of reasons that were outside protocols at unknown times and were mostly outside of study protocol. Cluster 2: Unplanned changes to study personnel early on that involved who was involved and were mostly outside of study protocol. Cluster 3: Unplanned changes to practice processes (recruitment and scheduling) early on to improve reach/engagement. Cluster 4: Unplanned program content changes for a variety of reasons at a variety of times that were within protocol. Cluster 5: Unplanned reactionary changes throughout the implementation to improve feasibility that largely affected who was involved. Cluster 6: Unplanned changes to follow-up or tracking with the goal of improving feasibility through the implementation process

From: Methods for capturing and analyzing adaptations: implications for implementation research