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Table 1 Characteristics of ACS patients stratified by management strategy

From: Impact of provincial and national implementation strategies on P2Y12 inhibitor utilization for acute coronary syndrome in the elderly: an interrupted time series analysis from 2008 to 2018

Characteristic

Medical management

n=49,652

PCI

n=56,358

CABG

n=8,132

p value

Age*

75.71 ± 6.50

75.71 ± 6.94

74.11 ± 5.63

<.001

Male sex (%male)

30,742 (61.9%)

35,137 (62.3%)

5973 (73.5%)

<.001

Current smoker

6521 (13.1%)

8010 (14.2%)

1272 (15.6%)

NS

Previous smoker

17,301 (34.8%)

16,532 (29.3%)

2866 (35.2%)

<.001

COPD

5276 (10.6%)

4552 (8.1%)

598 (7.4%)

<.001

CVD

5723 (11.5%)

5240 (9.3%)

809 (9.9%)

<.001

CHF

7157 (14.4%)

4962 (8.8%)

812 (10.0%)

<.001

Diabetes

18,193 (36.6%)

16,737 (29.7%)

2855 (35.1%)

<.001

Hyperlipidemia

37,018 (74.6%)

34,964 (62.0%)

5418 (66.6%)

<.001

Hypertension

39,566 (79.7%)

40,309 (71.5%)

6025 (74.1%)

<.001

History of MI

18,988 (38.2%)

15,950 (28.3%)

1947 (23.9%)

<.001

PVD

5583 (11.2%)

4,533 (8.0%)

839 (10.3%)

<.001

Renal disease

261 (0.5%)

215 (0.4%)

31 (0.4%)

NS

Previous CABG

10,643 (21.4%)

8042 (14.3%)

251 (3.1%)

<.001

Previous PCI

11,722 (23.6%)

12,284 (21.8%)

977 (12.0%)

<.001

Previous antithrombotic

 Dabigatran

744 (1.5%)

630 (1.1%)

58 (0.1%)

<.001

 Apixaban

779 (1.6%)

795 (1.4%)

66 (0.8%)

<.001

 Rivaroxaban

992 (2.0%)

1,156 (2.1%)

116 (1.4%)

<.001

 Warfarin

4,894 (9.9%)

3,700 (6.6%)

396 (4.9%)

<.001

 Prasugrel

21 (0.0%)

36 (0.1%)

0 (0.0%)

NS

 Clopidogrel

11,575 (23.3%)

10,614 (18.8%)

1029 (12.7%)

<.001

 Ticagrelor

589 (1.2%)

992 (1.8%)

45 (0.6%)

<.001

  1. *Mean ± SD
  2. Abbreviations: COPD Chronic obstructive pulmonary disease, CVD Cerebrovascular disease, CHF Congestive heart failure, MI Myocardial infarction, PVD Peripheral vascular disease, CABG Coronary artery bypass grafting surgery, PCI Percutaneous coronary intervention
  3. The baseline characteristics, including medical co-morbidities and previous antithrombotic use, were measured when patient presented with their ACS