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Table 2 Adjusted odds ratio and 95% confidence intervals for the primary and secondary outcomes

From: The effectiveness of generic emails versus a remote knowledge broker to integrate mood management into a smoking cessation programme in team-based primary care: a cluster randomised trial


No. (%) in group A (knowledge broker)

No. (%) in group B (monthly emails)

Intra-cluster correlation coefficientb

Adjusted odds ratioc (95% CI)

P value

Primary: Patient accepted the mood resource at enrollment (n = 2763)

437/1486 (29)

345/1277 (27)


0.93 (0.60, 1.43)


Secondary: Patient quit smoking at 6-month follow-up (n = 2136)

345/1160 (30)

279/976 (29)


1.11 (0.91, 1.35)


  1. aThe primary outcome was derived from healthcare providers’ response to the online STOP portal prompt at patient enrollment. The secondary outcome was measured at patients’ 6-month follow-up. The secondary outcome model was limited to patients who responded to the 6-month outcome survey
  2. bBased on unadjusted models
  3. cBoth models were adjusted for study stratification variables (organisational readiness and size) and the following patient-level variables measured at enrollment: age; gender; self-reported First Nations, Inuit or Métis status; employment status; education level; household income; smoking status; willingness to quit smoking in the next 30 days; past year alcohol use; past 30-day marijuana use; past 30-day opioid use; sum PHQ-9 score and self-reported lifetime history of depression, anxiety, schizophrenia, bipolar disorder, substance use disorder, alcohol use disorder and problem gambling