Table 2 Trial outcomes
Type | Outcome | Data source | Definition | When outcome is analyzed |
|---|---|---|---|---|
Primary | Reduction in inappropriate prescribing | EHR | Composite of (1) discontinuation of high-risk medications or (2) ordering a gradual dose taper | End of stages 1 and 2 |
Secondary | Quantity of prescribing | EHR | Number of milligram equivalents of high-risk medications prescribed to patients | End of stage 2 |
Tertiary | Quantity of medication dispensed | Administrative claims | Number of milligram equivalents of high-risk medications filled by patients | End of stage 2 |
Adverse events | Administrative claims | Occurrence of clinically significant adverse drug events, such as all-cause hospitalizations, falls, and fractures | End of stage 2 |