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Table 1 Published randomized controlled trials with moderate- to high-certainty evidence

From: Implementation and evaluation of nonclinical interventions for appropriate use of cesarean section in low- and middle-income countries: protocol for a multisite hybrid effectiveness-implementation type III trial

Study

Study design

Type of intervention

Overall CS rate in %

Relative effect (95% CI)

Intervention

Control

Baseline

Post

Baseline

Post

Lomas [12]

Cluster RCT

Opinion leader education

 

53.7*

 

66.8*

Not reported

 

Audit and feedback

69.7*

66.8*

Althabe [13]

Cluster RCT

Mandatory second opinion

26.3

24.7

24.6

24.9

ARR −1.9 (−3.8 to −0.1)

Chaillet [14]

Cluster RCT

Audit and feedback

22.5

21.8

23.2

23.5

ARR −1.8 (−3.8 to −0.2)

RCT

8.5**

7.6**

8.5**

9.0**

ARR −1.7 (−3.0 to −0.3)

Mansoumi [15]

RCT

Antenatal education program for physiologic childbirth

 

45.0

 

43.7

RR 1.03 (0.72 to 1.49)

Bergstrom [16]

RCT

Antenatal education on natural childbirth preparation with training in breathing and relaxation techniques

 

59.9*

 

63.0*

RR 0.95 (0.58 to 1.56)

Fraser [17]

RCT

Individualized prenatal education and support program versus written information in pamphlet

 

21.3

 

23.7

RR 0.90 (0.74 to 1.11)

Montgomery [18]

RCT

Computer-based decision aids (information program, decision analysis)

 

48.6*

 

49.6*

RR 0.98 (0.82 to 1.18)

Shorten [19]

RCT

Decision aid booklet during antenatal care

 

49.4*

 

52.2*

Not reported

Bohren [11]

Meta-analysis

Companionship during labor

 

12.3

 

15.0

RR 0.75 (0.64 to 0.88)

  1. RCT randomized controlled trial with intervention at the woman’s level; cluster-RCT randomized controlled trial with intervention at the hospital or healthcare provider level
  2. For RCTs, risk ratio (RR) = (mean rate intervention/mean rate control) with 95% confidence intervals
  3. For the meta-analysis of RCTs, the relative effect is the summary risk ratio with 95% confidence intervals
  4. For cluster-RCTs, absolute risk reduction (ARR) = (rate change in the intervention group)—(rate change in the control group) with 95% confidence intervals
  5. *The selected outcome is the elective repeat cesarean section rate among high-risk women (women with previous CS)
  6. **The selected outcome is the overall CS rate among low-risk women (single pregnancy with cephalic presentation without any complication)