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Table 1 Targeted barriers and content of 3HP delivery strategies

From: Protocol for the 3HP Options Trial: a hybrid type 3 implementation-effectiveness randomized trial of delivery strategies for short-course tuberculosis preventive therapy among people living with HIV in Uganda

Capability

Opportunity

Motivation

Selected intervention function(s)

Selected behavior change technique

Selected

mode of delivery

Knowledge

Capacity to remember

Capacity to plan

Time to access 3HP

Cost to access 3HP

Inadequate support

Beliefs about consequences

Self-efficacy

Lack of cues/reminders

   

Facilitated directly-observed therapy (DOT)

✓

     

✓

  

Education, persuasion

Information about health consequences

Standardized counseling by clinic nurse

   

✓

✓

    

Environmental restructuring

Restructuring physical environment

Streamlined weekly clinic visits + cost reimbursement

 

✓

      

✓

Enablement

Prompts/cues

Appointment reminders via Interactive Voice Response (IVR)

✓

    

✓

✓

✓

 

Education, persuasion

Credible source

Weekly visit with health worker (DOT)

Facilitated self-administered therapy (SAT)

✓

     

✓

  

Education, persuasion

Information about health consequences

Standardized counseling by clinic nurse

   

✓

✓

    

Environmental restructuring

Restructuring physical environment

SAT + streamlined monthly clinic visits + cost reimbursement

 

✓

✓

     

✓

Enablement

Prompts/cues

Dosing reminders and confirmation via IVR

     

✓

 

✓

 

Enablement

Social support

Weekly check-in via IVR

Patient choice between facilitated DOT and facilitated SAT

✓

    

✓

✓

✓

 

Education, enablement

Problem solving

Shared decision-making, facilitated by decision aid