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Table 4 Characteristics of included studies

From: Clinicians’ attitudes and perceived barriers and facilitators to cancer treatment clinical practice guideline adherence: a systematic review of qualitative and quantitative literature

First author Sample size Response rate % Qual/Quanta Method MO RO Surg Urologist Others Cancer streamb Stage Country CPG focusc
O'Brien (2016) [54] 28 68% Qual Interview Y Y Y - Breast Positive SLNB Canada cALND after positive sentinel lymph node biopsy (SLNB) regional CPG
Shelton (2019) [55] 42 Qual Interview Y Y - Y Colon Stage II USA Adjuvant chemotherapy for colon cancer national CPGs (ASCO or the NCCN)
Otte (2017) [53] 14 Qual + Quant Interview including Q card sorting Y - Pancreatic ductal adeno-carcinoma Locally advanced, UICC Stage III cT4N1M0 Germany Exocrine pancreatic adenocarcinoma Treatment CPGs, including recommendations for active cancer treatment and treatment with palliative intent
Brouwers (2014) [56] 71 30% Qual + Quant Surveys + interviews Y Y Y - NSCLC Stage II/IIIA resected NSCLC and unresected stage IIA/B NSCLC Canada 1. CCOPGI Chemotherapy CPG: stage II/IIIA resected NSCLC patients 2. CCOPGI Chemotherapy + radiation: unresected stage IIIA/B NSCLC patients
Bristow (2018) [57] 128 - Quant Survey Y Y Y Prostate Post-Prostatectomy Canada ASTRO and AUA Adjuvant and salvage post prostatectomy radiotherapy CPGs
Brown (2016) [58] 157 45% Quant Survey Y Y Prostate Locally advanced Australia ACN Adjuvant radiotherapy treatment for prostate cancer CPG
Carrick (1998) [59] 150 64% Quant Survey Y - Breast Early stage Australia NHMRC Early breast cancer management CPG
Fonteyne (2018) [60] 126 18% Quant Survey Y Y Y Y MIBC Primary to metastatic Belgium Primary, Adjuvant and metastatic radiotherapy treatment for MIBC
Gattellari (2001) [61] 195 89% Quant Survey Y - CRC Australia ANC/COSA CRC management CPGs
Graham (2007) [15] 520 57% Quant Survey Y Y - Y Cancer Canada CCOPGI cancer management CPGs
Grilli (1991) [62] 770 41% Quant Survey Y Y - Y Breast, CRC, Ovarian Italy Italian National CPGs for Breast, CRC, and ovarian cancer treatment
Ismaila (2018) [63] 101 53% Quant Survey Y - Cancer Nigeria International, national, local oncology CPGs
Jagsi (2014) [64] 896 60% Quant Survey Y Y - Breast USA NCCN CPG for Breast cancer
Ward (1997) [65] 69 77% Quant Survey Y Y Y - Y Breast Early stage Australia NHMRC early breast cancer CPG
White (2010) [66] 63 (survey) 58% Quant Survey + Patterns of care study Y - Breast (DCIS) DCIS Australia Australian treatment recommendations for DCIS
  1. aQual qualitative research, Quant quantitative research, MO medical oncologist, RO radiation oncologist, Surg surgeon
  2. bcALND completion axillary lymph node dissection, CRC colorectal cancer, DCIS ductal carcinoma in situ, MIBC muscle invasive bladder cancer, NSCLC non-small cell lung cancer
  3. cACN Australian Cancer Network; AUA American Urological Association; ASCO American Society of Clinical Oncology; ASTRO The American Society for Radiation Oncology, CCOPGI Cancer Care Ontario, Practice Guideline Initiative; COSA Clinical Oncology Society of Australia; NCCN National Comprehensive Cancer Network; NHMRC National Health and Medical Research Council; SLNB sentinel lymph node biopsy