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Table 2 Sequences of implementation strategies

From: The Balanced Opioid Initiative: protocol for a clustered, sequential, multiple-assignment randomized trial to construct an adaptive implementation strategy to improve guideline-concordant opioid prescribing in primary care

Conditions (Fig. 2) Sequence of implementation strategies (A1, A2) Intervention months 0–3 Intervention months 4–9 Intervention months 10–21
A EM/AF only (− 1, − 1) EM/AF No PF EM/AF
B EM/AF + PPC (− 1,+ 1) EM/AF No PF EM/AF + PPC
C EM/AF + PF (+ 1,− 1) EM/AF Add PF EM/AF + PF
D EM/AF + PF + PPC (+ 1,+ 1) EM/AF Add PF EM/AF + PF + PPC