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Table 7 Model tested

From: A systematic review of empirical studies examining mechanisms of implementation in health

Study

Independent variable (X)

Intervening variable (M)

Dependent variable (Y)

Qualitative

Bardosh et al. 2017 [16]

Mobile and text follow up with patients

Service organization at clinic level, clinician norms and practices, availability of local champions staff, adaptability and co-design of strategy, receptivity and capacity of local management

Culture of care

Brewster et al. 2015 [17]

Patient education, follow-up phone calls to patients after discharge, discharge planning, collaboration with post-acute providers

Intrinsic reward to staff --> shift in norms and attitudes

Reduced hospital readmissions

Carrera and Lambooij 2015 [18]

None reported

Mediators: perceived usefulness, perceived ease of use, self-efficacy, attitudes,social norm

Moderator: enabling conditions

Intervention acceptability (providers and patients)

Frykman et al. 2014 [19]

Senior manager and consultant-driven teamwork strategy, senior manager and staff-driven teamwork strategy

Direction, communication, opportunity, motivation

Change in staff behavior

Wiener-Ogilvie et al. 2008 [20]

Guideline implementation

Practice organization (delegation of work to nurses)

Compliance with guidelines

Quantitative—randomized

Atkins et al. 2008 [21]

Training and consultation

Key opinion leader instrumental supportmental health professional instrumental support

Teacher self-reported used of ADHD guidelines

Baer et al. 2009 [22]

Climate for organizational change

Post training agency activities to support use of Motivational Interviewing

Fidelity to intervention (Motivational Interviewing spirit and response to question ratio)

Bonetti et al. 2005 [23]

Audit and feedback

Decision difficulty, behavioral control

Simulated behavior

Garner et al. 2011 [24]

Pay for performance

1. Subjective norms

2. Attitudes toward intervention

3. Perceived control

1. Therapists’ intention to achieve monthly competence

2. Therapists’ intention to achieve targeted threshold

Glisson et al. 2010 [25]

Availability responsiveness and continuity (ARC) Intervention + Multisystemic Therapy quality assurance, pay for performance

Fidelity to multisystemic therapy

Rate of change in child behavior out of home placements

Holth et al. 2011 [26]

Workshop + manual, intensive quality assurance + workshop + manual

Adherence to contingency management and cognitive behavioral therapy techniques

Youth cannabis use

Lee et al. 2018 [27]

Implementation strategy bundles (varied across studies)

Knowledge, skills, social/professional role and identity, environmental resources

Nutrition guideline implementation

Lochman et al. 2009 [28]

Intensive training + feedback, basic training

# of sessions attended, # of objectives completed, # of contacts with trainers, counselor engagement w/clients

Client externalizing behaviors, client social skills, client study skills, client expectancies re: aggression, consistent parenting, client assaultive acts

Rapkin et al. 2017 [29]

Indicators of program activities: cumulative local programs, attendance at local programs, time since most recent local program, personal awareness of programs, cumulative outside programs

Mediators: awareness of free/low cost cancer screening, cancer knowledge, cancer information seeking, having health insurance, annual physical moderator: frequency of library use

Cancer screening attempts to quit smokingtobacco cessation

Rohrbach et al. 1993 [30]

1. Teacher training

2. Principal support intervention

1a. Teacher self-efficacy, 1b. enthusiasm, 1c. preparedness

2a. Principal encouragement, 2b. Principal beliefs about program

Quantity of program implementation

Seys et al. 2018 [31]

Care pathway implementation

Adherence to evidence-based recommendations, level of competence, team climate for innovation, burnout, level of organized care

30-day hospital readmission

Williams et al. 2014 [32]

Information packets and Motivational Interviewing webinar

Attitudes towards EBPs, pressure for change, barriers to EBPs, resources, organizational climate, management support

Motivational Interviewing adoption

Williams et al. 2017 [33]

Availability,Responsiveness, and Continuity (ARC) intervention implementation

Proficiency culture --> evidence-based practice intention, barrier reduction

EBP adoption, EBP use

Quantitative—non-randomized

Aarons et al. 2009 [34]

Agency type

1. organizational support for EBP --> provider attitudes towards EBP

2, 3 organizational support for EBP organizational support for EBP

1,3 provider EBP use2. provider EBP attitudes

Becker et al. 2016 [35]

Training as usual, training + ongoing technical assistance, support from in-house champion, specialized training on change process, monthly conference calls and online forum to support change

Organizational readiness to change (motivation for change, adequacy of resources, staff attributes, organizational climate),perceived intervention characteristics (relative advantage, observability, trialability, compatibility, and complexity)

Adoption

Beenstock et al. 2012 [36]

Main place of work

Propensity to act

Referral of women to smoking cessation services

Beets et al. 2008 [37]

Perception of school climate

1. Beliefs about responsibility to teach program

2. beliefs about responsibility to teach program --> attitudes towards program --> curriculum delivered

1. Attitudes towards program

2. curriculum delivered to schoolwide material usage

Bonetti et al. 2009 [38]

Behavioral intention

Action planning

Placing fissure sealants

Chou et al. 2011 [39]

Receipt of individual performance feedback, clinician input into guideline implementation and quality improvement, clinician expectancy, clinician self-efficacy

Agreement with guidelines, adherence to guidelines, improved knowledge, practice delivery

Fidelity to screening patients for depression

Cummings et al. 2017 [40]

Culture, feedback, leadership and resources

Manager support, coaching conversations, job satisfaction

Conceptual research use, persuasive research use, instrumental research use

David and Schiff 2017 [41]

Child-parent psychotherapy social network

Child-parent psychotherapy supervision

Self-efficacy

Number of child-parent psychotherapy cases, intention to use child-parent psychotherapy

Edmunds et al. 2014 [42]

Time following training

Time spent in consultation

Knowledge of cognitive behavioral therapy for anxiety, attitudes towards EBPs

Gnich et al. 2018 [43]

Pay-per item financial incentive

Knowledge, skills, social/professional role and identity, beliefs about consequences, motivation and goals (intention), environmental context and resources, social influences (norms), emotion, behavioral regulation

Fluoride varnish delivery

Guerrero et al. 2018 [44]

Top manager transformational leadership

Middle managers’ implementation leadership

Employee attitudes towards EBPs, EBP implementation

Huis et al. 2013 [45]

individual and organization targeted strategies (education, reminders, feedback), individual and organizational targeted strategies + team and leader strategy

Social influence, leadership, performance feedback

Handwashing fidelity

Little et al. 2015 [46]

Community priority, organizational support, program champion

beliefs about effectiveness of interventions --> funding to adopt program

Adoption

Llasus et al. 2014 [47]

EBP knowledge

Self confidence in one's EBP competencies (defined as readiness)

EBP implementation behaviors

Nelson and Steele 2007 [48]

EBP training, openness of clinical setting to EBPs

Positive attitudes towards treatment research, negative attitudes towards treatment research

EBP use

Potthoff et al. 2017 [49]

Action planning, coping planning

Habit

Clinical behaviors (prescribing, advising, examining)

Presseau et al. 2016 [50]

Printed informational materials

Attitudes toward prescribing, subjective norms, perceived behavioral control, intention to prescribe

Self-reported prescribing behavior

Simmonds et al. 2012 [51]

Intolerance of uncertainty

Treatment orientation toward back pain

Recommendations to return to work

2. recommendations to return to usual activities,estimated risk of back pain disability

Stockdale et al. 2018 [52]

Health care team communication

Patient-provider communication

Patient satisfaction with primary care provider

Wanless et al. 2015 [53]

Use of responsive classroom practices, global emotional support, self-efficacy, collective responsibility

Teacher training engagement

Fidelity to intervention

Yamada et al. 2017 [62]

Instrumental research use, conceptual research use

Organizational context:

leadership, culture, evaluation, social capital, informal interactions, formal interactions, resources, slack space, slack staff, slack time

Pain assessment, evidence-based pain procedure use, pain intensity

Mixed methods

Armson et al. 2018 [54]

Implementation tools (printed education materials, informational video, decision aid)

Evidence-based information in guideline, evidence-based information in screening module, discussions with peers, application of implementation tools, discussions with patients, lack of evidence about benefits, patients' screening expectations, fear of misdiagnosis, problems with having patient materials available

Use of breast cancer screening guidelines

Birken et al. 2015 [55]

1. Top manager support

2. Performance reviews

3. Human resources

Mediators:

1a. Performance reviews

1b. Human resources

1c. Training

1d. Funding

1e. Local social network involvement

Moderator:

2/3. top manager support

1, 2, 3 middle manager commitment to innovation

Kauth et al. 2010 [56]

Facilitation + workshop, workshop

Job-related barriers, # of contacts with facilitator,

time spent in facilitation

% time conducting Cognitive Behavioral Therapy

Lukas et al. 2009 [57]

Higher management support, group culture, hierarchical culture

Team effectiveness

Extent of implementation

Panzano et al. 2012 [58]

1. Strategic fit of intervention

2. Climate for innovation

1. Climate for innovation2. Fidelity to intervention

1. Fidelity to intervention

2. Assimilation

Rangachari et al. 2015 [59]

Emails containing intervention information and unit level adherence feedback + brief weekly training

Proactive communication between nurses and physicians emergence of champions

Number of catheter days

Shrubsole et al. 2018 [60]

Tailored training intervention targeting information provision

Mechanisms of Intervention 1 targeting information provision implementation):

knowledge, beliefs about consequences, social influence, beliefs about capabilities, environmental context and resources

Mechanisms of Intervention 2 targeting implementation of goal setting): beliefs about consequences, social influences, beliefs about capabilities, environmental context and resources

Information provisiongoal setting

  1. Numbering is used to denote match variables across models; not all models tested the same sets of variables