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Table 5 Change differences between groups in a subgroup of patients with a mean HbA1c > 7%, a subgroup of patients with a mean LDL cholesterol > 100 mg/dL and a subgroup of patients with a mean blood pressure > 130/80 mg/dL

From: Computerized clinical decision support system for diabetes in primary care does not improve quality of care: a cluster-randomized controlled trial

 Control Estimated mean (95% CI)Intervention Estimated mean (95% CI)Change difference IG-CG Estimated mean (95% CI)
HbA1c > 7%1
 Baseline (BL)7.99 (7.65; 8.33)8.27 (7.91; 8.63) 
 6 months (6M)7.78 (7.43; 8.14)8.11 (7.73; 8.49)
 12 months (12M)7.64 (7.31; 7.98)7.53 (7.17; 7.89) 
Change BL–6M− 0.21 (− 0.43; 0.02)− 0.16 (− 0.42; 0.09)0.04 (− 0.29;0.38)
Change BL–12M− 0.35 (− 0.54; − 0.15)− 0.75 (− 0.98; − 0.51)− 0.40 (− 0.70; − 0.09)
Systolic blood pressure > 130 mmHg2
 Baseline147.11 (144.67; 149.55)147.77 (145.10; 150.44) 
 6 months143.75 (141.25; 146.25)144.94 (142.10; 147.78) 
 12 months141.08 (138.56; 143.60)141.68 (138.89; 144.47) 
Change BL–6M− 3.36 (− 4.58; − 2.14)− 2.83 (− 4.50; − 1.16)0.53 (− 1.54; 2.60)
Change BL–12M− 6.03 (-7.49; − 4.57)− 6.09 (− 7.89; − 4.28)0.06 (− 2.39; 2.27)
Diastolic blood pressure > 80 mmHg3
 Baseline87.39 (85.85; 88.93)87.16 (85.47; 88.86) 
 6 months84.00 (82.46; 85.55)85.11 (83.31; 86.92) 
 12 months82.64 (81.09; 84.19)83.29 (81.56; 85.02) 
Change BL–6M− 3.39 (− 4.37; − 2.41)− 2.05 (− 3.44; − 0.66)1.34 (− 0.37; 3.04)
Change BL–12M− 4.75 (− 5.74; − 3.76)− 3.88 (− 5.09; − 2.66)0.87 (− 0.69; 2.44)
LDL cholesterol > 100 mg/dL4
 Baseline131.32 (128.29; 134.34)128.84 (124.92; 132.77) 
 6 months126.88 (123.46; 130.31)124.40 (119.93; 128.86) 
 12 months118.28 (114.73; 121.82)115.94 (111.05; 120.82) 
Change BL–6M− 4.43 (− 6.17; − 2.69)− 4.44 (− 6.89; − 1.99)− 0.01 (− 3.01; 2.99)
Change BL–12M− 13.04 (− 15.64; − 10.44)− 12.91 (− 17.14; − 8.67)0.14 (-4.84;5.11)
  1. 1Subgroup analysis based on 601 patients
  2. 2Subgroup analysis based on 566 patients
  3. 3Subgroup analysis based on 566 patients
  4. 4 Subgroup analysis based on 879 patients