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Table 1 (abstract P41). Example CFIR construct, barriers, solutions, and outcome (adapted from Stark et al1)

From: Proceedings from the 2nd Annual UK Implementation Science Research Conference, 'Advancing the science of scaling up: Improving efficiency and effectiveness of implementation strategies in healthcare': meeting abstracts

CFIR construct

Barrier

Enabler identified

Outcome

Networks & Communications

Delay in referral to clinical genetics

Clearly communicate availability of rapid genomic testing and indications for referral

Earlier referrals to clinical genetics

Relative advantage

Ensure referrers get feedback on diagnostic and clinical impact of rapid genomic testing, e.g. at monthly NICU/Genetics case review meetings

Increased number of referrals to clinical genetics

Implementation climate

Parental difficulty processing complex information in a stressful environment

Increased genetic counselling support in the acute setting

Higher rate of rapid genomic testing acceptance by families

Adaptability

Results batched ready for weekly dedicated MDT meeting

Initiate multidisciplinary team meetings for single cases, with minimum quorum defined

Reduction in time to report

Formal implementation leaders

Absence of an established

rapid genomic testing pathway

Clinical and laboratory champions identified

Formal rapid genomic testing operating procedure

established

  1. Interviews for the multi-state trial are ongoing. Early findings indicate the importance of relationships between genetic and paediatric intensivist staff