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Table 3 Summary of included studies and quality appraisal—panel a improvement studies; panel b implementation studies

From: Use of health economic evaluation in the implementation and improvement science fields—a systematic literature review

Author Year Country Improvement or implementation focus Care setting Improvement intervention focus Sample size Main study outcomes Type of economic analysis Quality appraisal score for economic modelling (out of 100)
a: Improvement studies
 Afzali et al 2013 Australia Improvement Endocrinology Staff mix reformulation (nurse-led) 3642 EQ-5D (EuroQol 5 dimension scale) CEA 100
 Albers-Heitner et al 2010 Netherlands Improvement Primary Care Staff mix reformulation (nurse-led) 384 EQ-5D CEA 74
Bauer 2010 USA Improvement N/A Staff mix reformulation (nurse-led) 160 Resource use CEA N/A
 Dawes et al 2007 UK Improvement Gynaecology Staff mix reformulation (nurse-led) 111 SF-36 (36-Item Short Form Health Survey), Length of Stay CCA 66.5
 Faulkener et al 2003 UK Improvement Primary Care Improved referral N/A Review Review N/A
 Furze et al 2011 UK Improvement Cardiology Staff mix reformulation (peer support) 142 EQ-5D CUA 84.5
 Hernandez et al 2014 UK Improvement Intensive Care Staff mix reformulation (nurse-led) 286 EQ-5D CUA 90.5
 Karnon et al 2016 Australia Improvement Cardiology Service Reconfiguration (funding sources) 603 N/A CCA 44.5
 Kilpatrick et al 2014 Canada Improvement Hospital General Medicine Staff mix reformulation (nurse-led) 2147 Review CEA N/A
 Latour et al 2007 Netherlands Improvement Hospital wards Staff mix reformulation (nurse-led) 208 SF-36, HADS (Hospital Anxiety and Depression Scale) CEA 81.5
 Mdege et al 2012 Sub-Saharan Africa Improvement HIV Staff mix reformulation (multiple scenarios) 19,767 N/A Review N/A
 Tappenden et al 2012 UK Improvement Geriatrics Staff mix reformulation (nurse-led) N/A Review CEA N/A
 Walsh et al 2005 UK Improvement General Medicine Staff mix reformulation (nurse-led) 238 Bed days CA 65
 Williams et al 2006 UK Improvement Gastroenterology Staff mix reformulation (nurse-led) 1500 EQ-5D CEA 94
 Williams et al 2005 UK Improvement Urology Staff mix reformulation (nurse-led) 3746 EQ-5D CEA 51
 Yarbrough et al 2015 USA Improvement General Medicine New pathway 677 Resource use CEA N/A
b: Implementation studies
Author Year Country Improvement or implementation focus Care setting Implementation intervention focus Main study outcomes Type of economic evaluation Sample size Quality appraisal score for economic modelling (out of 100)
 Brunenberg et al 2005 Netherlands Implementation Orthopaedics Pathway implementation EQ-5D, Length of stay CEA 160 71
 Burr et al 2007 UK Implementation Ophthalmology Screening programme implementation EQ-5D CUA 207–32,918 89.5
 Burr et al 2012 UK Implementation Ophthalmology Surveillance programme implementation EQ-5D, Willingness to pay CUA 800 92.5
 Judd et al 2014 USA Implementation Hospital wards Early intervention implementation Length of Stay CA 181 37
 Kifle et al 2010 Ethiopia Implementation All hospital specialities Referral system implementation Resource use CEA 532 N/A
 Maloney et al 2012 Australia Implementation Physiotherapy Health professional education Costs only CEA 85 94.5
 Mortimer et al 2013 Australia Implementation General Practice Implementation methods (active vs guideline dissemination) EQ-5D, X rays avoided CEA 112 81.5
 Purshouse et al 2013 UK Implementation Public Health Screening programme implementation EQ-5D CEA N/A 82
 Rachev 2015 USA Implementation Public Health General methods of health service transformation Resource use CEA N/A N/A
 Robertson et al 2011 UK Implementation Oncology Surveillance programme implementation EQ-5D CUA N/A 94
 Tappenden et al 2013 UK Implementation Oncology Resource allocation decision making EQ-5D CUA N/A 84
 Umscheid et al 2010 Canada Implementation N/A Comparative effectiveness centre None Review N/A N/A
 Vestergaard et al 2015 Denmark Implementation Cardiology Guideline adherence vs observed treatment EQ-5D CEA N/A 57.5
 Yee and Shafie 2013 Malaysia Implementation Respiratory Asthma management implementation EQ-5D Review N/A N/A