The checklist contains four CDS domains (Fig. 1). Each domain includes four factors, making 16 factors in total (see Fig. 2). Checklist domains:  • Context: the circumstances in which CDS can be potentially successful.  • Content: the factors shaping the success of the advice produced by the CDS system.  • System: features belonging to the CDS tool.  • Implementation: factors affecting the integration of CDS into practice settings. The full checklist (see Additional file 3) provides:  • A rationale for the importance of each factor.  • Sample questions to consider.  • Positive and negative examples. The GUIDES checklist is available in different formats, including an electronic version that enables CDS implementation teams to complete the GUIDES checklist efficiently in a group |