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Table 2 Patients’ outcomes by study phase

From: A multidisciplinary team-oriented intervention to increase guideline recommended care for high-risk prostate cancer: A stepped-wedge cluster randomised implementation trial

Characteristic

Referred1

Discussed2

Consultation3

n/N (%)

Adjusted # RR (95% CI)

n/N (%)

Adjusted # RR (95% CI)

n/N (%)

Adjusted # RR (95% CI)

All patients:

325/1071 (30%)

 

354/1071 (33%)

 

278/1071 (26%)

 

Study phase

 Control

154/505 (30%)

ref.

88/505 (17%)

ref.

138/505 (27%)

ref.

 Transition

41/159 (26%)

0.99 (0.68, 1.46)

26/159 (16%)

1.52 (0.90, 2.58)

33/159 (21%)

0.99 (0.72, 1.35)

 Intervention

130/407 (32%)

1.06 (0.74, 1.51)

240/407 (59%)

4.32 (2.40, 7.75)

107/407 (26%)

1.05 (0.74, 1.51)

p value

 

0.879

 

< 0.001

 

0.896

  1. 1Patient referred within 4 months after prostatectomy to either a radiation oncologist or to the RAVES trial
  2. 2Patient discussed at MDT meeting within 4 months after prostatectomy
  3. 3Patient had consultation with radiation oncologist within 6 months after RP following referral within 4 months after RP
  4. #Adjusted for age at prostatectomy (40–59, 60–69, 70+), extracapsular extension (no, yes, unsure), positive surgical margin (no, yes, unsure), seminal vesicle invasion (no, yes, unsure), regional lymph node involvement (no, yes, unsure), post-operative Gleason score (6–7, 8, 9–10, unsure), maximum PSA level within 4 months after RP (< 0.1 ng/ml, ≥ 0.1 ng/ml, no PSA test recorded), number of co-morbidities (0, 1, 2, 3+), site (1 through 9), calendar time period of surgery (four time periods) and urologist as the GEE clustering variable
  5. 19 patients with “unsure” extracapsular extension, positive surgical margin and/or seminal vesicle invasion were excluded from regression analysis because low numbers in those groups prevented model convergence