Table 1 Evolution of SPPiRE from OPTI-SCRIPT
| Â | OPTI-SCRIPT [28] | SPPiRE |
|---|---|---|
Population | Research pharmacist determined if identified older patients had a PIP | Identified by patient finder tool as being prescribed ≥15 repeat medicines |
Intervention | Academic detailing by research pharmacist | Training video by research GP |
Web-guided medication review  • Provided with alternative pharmaceutical treatment algorithms for PIP | Web-guided medication review  • Guided to check for specific PIP  • Guided to tailor care to patient’s priorities | |
Primary outcomes | Proportion of patients with PIP | Proportion of patients with PIP |
| Â | Mean number of PIPs per patient | Number of repeat medications |
Secondary outcomes | Drug specific outcomes | Medication changes |
Patient-reported outcomes • Quality of life • Patient’s medication beliefs • Patient well being | Patient-reported outcomes  • Quality of life  • Patient’s attitudes to deprescribing  • Treatment burden |