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Table 1 Secondary prescribing outcomes from interim analysis

From: Improving the appropriateness of antipsychotic prescribing in nursing homes: a mixed-methods process evaluation of an academic detailing intervention

Interim prescribing outcomes Academic detailing intervention Usual care
Baseline 3 months 6 months Baseline 3 months 6 months
Per protocol n = 2820 n = 2914 n = 2947 n = 3934 n = 4093 n = 4162
 Antipsychotic daily dose in the past 28 days (mean ± SD)a 120 ± 155 116 ± 136 122 ± 152 127 ± 156 133 ± 160 125 ± 156
 Antipsychotic [n(%)] 639 (22.7%) 630 (21.6%) 624 (21.2%) 890 (22.6%) 903 (22.1%) 898 (21.6%)
 Acetaminophen [n(%)] 1237 (43.9%) 1263 (43.3%) 1244 (42.2%) 1677 (42.6%) 1749 (42.7%) 1736 (41.7%)
 Antidepressant [n(%)] 1436 (50.9%) 1478 (50.7%) 1495 (50.7%) 2000 (50.8%) 2085 (50.9%) 2102 (50.5%)
 Benzodiazepine [n(%)] 261 (9.3%) 275 (9.4%) 273 (9.3%) 427 (10.9%) 469 (11.5%) 414 (9.9%)
As-treated n = 2342 n = 2421 n = 2453 n = 4412 n = 4586 n = 4656
 Antipsychotic daily dose in the past 28 days (mean ± SD)a 118 ± 151 114 ± 132 117 ± 145 128 ± 158 132 ± 160 128 ± 159
 Antipsychotic [n(%)] 556 (23.7%) 548 (22.6%) 535 (21.8%) 973 (22.1%) 985 (21.5%) 987 (21.2%)
 Acetaminophen [n(%)] 992 (42.4%) 1,006 (41.6%) 988 (40.3%) 1,922 (43.6%) 2,006 (43.7%) 1,992 (42.8%)
 Antidepressant [n(%)] 1160 (49.5%) 1200 (49.6%) 1210 (49.3%) 2276 (51.6%) 2363 (51.5%) 2387 (51.3%)
 Benzodiazepine [n(%)] 232 (9.9%) 243 (10.0%) 238 (9.7%) 456 (10.3%) 501 (10.9%) 449 (9.6%)
  1. aAmong those who used continuously