Fig. 1

Flowchart. Sixty general practices were included in the study. A total of 55 practices (28 MuIS, 27 PaIS) assigned 1152 patients (566 MuIS, 586 PaIS) for assessment of eligibility. Fifty-four practices (28 MuIS, 26 PaIS) included and contributed with 1101 patients to the analysis for the primary outcome