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Table 2 Objective 1 outcomes and measures

From: Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial

Outcome Measure Method
Primary outcome
 Healthcare-associated infection (HAI) rates in each trial site Numbers of Staphylococcus aureus bacteraemia (SAB), Clostridium difficile infection (CDI) and clinical isolates of vancomycin resistant enterococci (VRE) and monthly rates per 10,000 occupied bed days Datasets include all patients across the hospital with a HAI, and data on occupied bed days
Collated from:
- Hospital infection data and reports for ongoing surveillance
- Hospital occupied bed days reports
Secondary outcome
 Hospital cleaning performance—thoroughness of hospital cleaning in each trial site Number and percentage of ultraviolet (UV) gel dots removed completely following cleaning DAZO® Fluorescent Marking Gel dots applied to frequent touch sites around two patient cubicle and bathroom areas in the intensive care unit (ICU) and the highest risk wards
Other outcomes—study specific data set
 Bio-burden of frequent touch surfaces post cleaning Levels of organic matter in relative light units (RLUs) post cleaning in three hospitals Adenosine tri-phosphate (ATP) bioluminescence measurements
Other outcomes—study specific data set
 Changes in staff knowledge and attitudes around environmental cleaning Pre-intervention educational needs. Pre- and post-intervention knowledge and attitudes about environmental cleaning and job roles Environmental services staff questionnaires and discussion groups
Other outcomes—existing data set
 Changes in rates of screening and clinical isolates Numbers of positive clinical isolates of other multi-resistant organisms per 1000 patient days at risk Collated from hospital infection data and reports, where available for ongoing surveillance and supplied to project team by trial site team
Other outcomes—existing data set
 Changes in patients’ perception of hospital cleanliness Patients’ perceptions of cleanliness Collated from existing hospital-based survey data, where available and supplied to project team by trial site team