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Table 2 Key sample size assumptions

From: Action to Support Practices Implement Research Evidence (ASPIRE): protocol for a cluster-randomised evaluation of adaptable implementation packages targeting ‘high impact’ clinical practice recommendations in general practice

  Atrial fibrillation Blood pressure control Risky prescribing Diabetes control
Mean number of patients per practice (cluster size) 55 800 420 280
Coefficient of variation (CV) of cluster size 0.79 0.67 0.65 0.6
Intra-cluster correlation coefficient (ICC) 0.06 0.06 0.03 0.06
Control group adherence 0.6 0.72 0.89 0.43