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Table 2 Pre- and post-workshop comparisons of maternal and neonatal characteristics

From: The effect of professional-led guideline workshops on clinical practice for the management of patent ductus arteriosus in preterm neonates in Japan: a controlled before-and-after study

 

Intervention NICUs (N= 2)

Control NICUs (N= 88)

Variables

Pre-WS (n = 146)

Post-WS (n = 148)

p value

MD or OR (95% CI)

Pre-WS (n = 3,322)

Post-WS (n = 2,912)

p value

MD or OR (95% CI)

Maternal age (years)

31.2 ± 5.1

31.6 ± 5.4

0.56

0.43 (−0.78, 1.64)

31.2 ± 5.2

31.4 ± 5.3

0.37

0.12 (−0.15, 0.39)

Missing

1

0

  

166

47

  

Primipara

121 (82.9)

116 (78.4)

0.32

0.75 (0.42, 1.34)

2,836 (85.4)

2,514 (86.3)

0.27

1.08 (0.94, 1.25)

Multiple pregnancy

42 (28.8)

40 (27.0)

0.73

0.92 (0.55,1.53)

834 (25.1)

681 (23.4)

0.11

0.91 (0.81, 1.02)

Maternal hypertension

22 (15.1)

25 (16.9)

0.67

1.15 (0.61, 2.14)

625/3,320 (18.8)

589/2,815 (20.9)

0.04

1.14 (1.01, 1.29)

Maternal diabetes

3 (2.1)

3 (2.0)

0.98

0.99 (0.20, 4.97)

44/3,320 (1.3)

52/2,749 (1.9)

0.08

1.44 (0.96, 2.15)

PROM

51 (34.9)

47 (31.8)

0.56

0.87 (0.53, 1.41)

896/3,322 (26.9)

866/2,888 (30.0)

<0.01

1.16 (1.04, 1.29)

Chorioamnionitis

19/146 (13.0)

46/146 (31.5)

<0.01

3.08 (1.70, 5.58)

494/3,271 (15.1)

467/2,652 (17.6)

<0.01

1.20 (1.05, 1.38)

Antenatal steroids use

80/146 (54.8)

97/147 (66.0)

0.05

1.6 (0.998, 2.57)

1,446/3,320 (43.6)

1,474/2,827 (52.1)

<0.01

1.41 (1.28, 1.56)

Gestational age (weeks)

28.2 ± 3.6

28.4 ± 3.2

0.67

0.19 (−0.58, 0.98)

28.4 ± 3.2

28.3 ± 3.2

0.82

−0.02 (−0.14, 0.18)

Birth weight (grams)

1,001.2 ± 323.9

991.7 ± 322.3

0.8

−9.53 (−83.6, 64.5)

1,027.2 ± 303.6

1,032.7 ± 301.7

0.47

5.53 (−9.53, 20.59)

Birth length (cm)

34.8 ± 4.1

34.4 ± 4.5

0.45

−0.38 (−1.39, 0.62)

35.3 ± 4.0

35.3 ± 4.2

0.85

0.02 (−0.19, 0.23)

Missing

4

1

  

232

158

  

Head circumference (cm)

25.2 ± 2.7

25.4 ± 3.3

0.5

0.24 (−0.46, 0.95)

25.6 ± 2.8

25.6 ± 2.9

0.9

−0.01 (−0.16, 0.14)

Missing

8

1

  

296

188

  

Gender (male)

80 (54.8)

72 (48.7)

0.29

0.78 (0.49, 1.24)

1,670/3,322 (50.3)

1,505/2,911 (51.7)

0.26

1.06 (0.96, 1.17)

Outborn

9 (6.2)

5 (3.4)

0.26

0.53 (0.17, 1.63)

245 (7.4)

225 (7.7)

0.6

1.05 (0.87, 1.27)

Vertex presentation

95/146 (65.1)

100/144 (69.4)

0.42

1.22 (0.75, 1.99)

2,258/3,309 (68.2)

1,859/2,658 (70.0)

0.15

1.08 (0.97, 1.21)

Cesarean section

110 (75.3)

105 (70.9)

0.39

0.80 (0.48, 1.34)

2,502 (75.3)

2,268 (77.9)

0.02

1.15 (1.03, 1.30)

Apgar score < 7 at 5 min

36/145 (24.8)

36/148 (24.3)

0.92

0.97 (0.57, 1.66)

801/3,219 (24.9)

682/2,863 (23.8)

0.33

0.94 (0.84, 1.06)

  1. Chi-square, Fisher’s exact test, or t-test was used as appropriate. p value <0.05 was considered statistically significant. All the estimates were rounded. Binary outcome variables with missing data are indicated by the denominators showing the numbers of assessed infants. MD mean difference, OR odds ratio, CI confidence intervals. MD or OR estimates correspond as appropriate. Unless otherwise stated, values represent number of neonates with their percentages in the parentheses. NICUs neonatal intensive care units, PROM premature rupture of the membrane; Pre-WS: before the workshops; Post-WS: after the workshops.