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Table 2 Situations that might necessitate the updating of a clinical practice guideline

From: Developing clinical practice guidelines: reviewing, reporting, and publishing guidelines; updating guidelines; and the emerging issues of enhancing guideline implementability and accounting for comorbid conditions in guideline development

1.  Changes in the evidence on the existing benefits and harms of interventions:
2.  Changes in the outcomes considered important:
3.  Changes in the available interventions:
4.  Changes in the evidence that current practice is optimal:
5.  Changes in the values placed on outcomes:
6.  Changes in the resources available for health care: