Strength of evidence*
Aspirin therapy (75-162 mg/day) indefinitely post-STEMI.
P2Y12-receptor inhibitor (clopidogrel, prasugrel, or ticagrelor) in combination with aspirin in patients post ACS
P2Y12-receptor inhibitor continued for at least 12 months if ACS managed with PCI and stent placement
Statin therapy indefinitely for all patients with a prior cardiovascular event.
ACE inhibitor (or ARB if intolerant) post-STEMI indefinitely for all patients with left ventricular ejection fraction <40% and in those with hypertension, diabetes, or chronic kidney disease
ACE inhibitor (or ARB) for all patients post-STEMI
Beta-blockers for all patients post-STEMI
Beta-blockers continued for at least three years post-STEMI