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Table 1 Studies describing guideline features that may influence use

From: How can we improve guideline use? A conceptual framework of implementability

Study

Design

Guideline features encouraging use

Brouwers

2009

Canada [48]

Survey of 756 physicians of various specialties between 1999 and 2005 on intended use of 84 cancer guidelines yielding 4,091 surveys

Strong supporting evidence, flexibility of recommendations to local context

Wakkee

2008

Netherlands [49]

Questionnaire of 261 dermatologists on characteristics of specific guideline

Concise recommendations

Nuckols

2008

United States [39]

Modified Delphi panel of 11 physicians of various specialties

Strong supporting evidence, flexibility of recommendations to patient needs and preferences

Francke

2008

Netherlands [7]

Meta-review of 12 systematic reviews on guideline implementation:

 
 

1. 41 cross sectional pre-/post-test studies or controlled trials

Easily accessible, strong supporting evidence, explicit resource implications, flexibility of recommendations to local

 

2. 76 survey and qualitative studies

 
 

3. 91 randomized, cross-over, balanced incomplete block design, controlled before/after, interrupted times series studies

context, concise recommendations

 

4. 61 mixed methods studies with focus on randomized or controlled trials

 
 

5. 23 studies of various quantitative designs

 
 

6. 235 randomized or controlled trials, controlled before/after or interrupted time series designs

 
 

7. 40 randomized or controlled trials or before/after studies

 
 

8. 15 randomized or controlled trials, pre-/post-test studies and one systematic review

 
 

9. 59 studies of various quantitative or qualitative or mixed design

 
 

10. 6 randomized controlled trials, time series or before/after studies and 8 studies of mixed design

 
 

11. 18 ranodmized or controlled trials, before/after or interrupted time series studies

 
 

12. 20 randomized or controlled trials, case series or case reports

 

Cochrane

2007

United States [30]

Systematic review of 256 studies of guideline implementation (178 surveys, 16 focus group studies, 18 interview studies, 44 mixed methods studies)

Easily accessible, strong supporting evidence, flexibility of recommendations to local context, concise recommendations

Carlsen

2007

Norway [50]

Qualitative analysis of six focus groups involving 27 general practitioners

Trustworthy, suit patients, recommended action is feasible

Carlsen

2007

Norway [42]

Systematic review of 12 qualitative studies (7 focus group studies, 5 interview studies) evaluating general practitioner attitudes about guidelines

Authorship familiarity, flexibility of recommendations to patient needs and preferences, short and concise, include patient leaflets

Jones

2007

Canada [51]

Qualitative analysis 28 interviews with physicians and nurses in four intensive care units

Easily accessible, accompanying tools such as checklists, strong supporting evidence, concise recommendations

Thomason

2007

United States [52]

Survey and focus groups with 60 physicians and nurses who attended a national conferences

Strong supporting evidence, concise recommendations

Sinuff

2007

Canada [53]

Qualitative analysis of interviews with 30 physicians and nurses at one hospital

Easily accessible, accompanying tools such as algorithms or pocket cards, concise recommendations

McKinlay

2004

New Zealand [54]

Qualitative analysis of interviews with 13 general practitioners from five sites

Authorship familiarity, variety of print and electronic formats

Shiffman

2003

United States [55]

Modified Delphi process involving representatives from 22 organizations active in guideline development

Explicit resource implications, suggestions for auxiliary documents for providers or patients, evaluative data collection tools

Price

2001

United States [56]

Discourse analysis of laboratory study using clinical scenarios and guidelines of different formats involving three general practitioners and three endocrinologists

Algorithmic guidelines were useful for clinical problem solving, textual guidelines were useful for learning

Vinker

2000

Israel [57]

Questionnaire of 293 general practitioners and family physicians participating in educational programs over two months

Strong supporting evidence, flexibility of recommendations to patient needs and preferences, concise recommendations

Harris

2000

United States [42]

Questionnaire and focus groups with an undisclosed sample drawn from 304 general practitioners based at 16 sites

Accompanying tools such as checklists and standard orders, summaries such as algorithms or diagrams, navigational support such as color-coded tabs, evaluative data collection tools, accessible by computer, information guides for patients

Shekelle

2000

United States [31]

Randomized controlled trial of questionnaire on intent to use guidelines among 545 general internists, neurologists and physical medicine specialists who received usual guideline or guideline modified with clinical vignettes

Clinical vignettes describing application of guidelines according to patient needs and preferences

Cabana

1999

United States [58]

Systematic review of 76 journal articles on barriers to guideline adherence among physicians

Strong supporting evidence, authorship familiarity, easily accessible, concise recommendations, flexibility of recommendations to patient needs and preferences

Grol

1998

Netherlands [37]

Observational study involving 12,880 decisions made by 61 general practitioners based on 12 guidelines with various attributes rated by participants

Strong supporting evidence, concise recommendations, explicit resource implications