Skip to main content

Table 2 Risk of bias of included studies

From: A systematic review of the effectiveness of interventions to improve post-fracture investigation and management of patients at risk of osteoporosis

Reference

Adequate sequence generation

Concealment of allocation

Blinded or objective assessment of primary outcome(s)

Adequately addressed incomplete outcome data

Free from selective reporting

Free from other risk of bias

Similar baseline characteristics

Similar baseline outcome measures

Adequate protection against contamination

Gardner 2005 [46]

Yes

Unclear

Unclear

Yes

Unclear - protocol not published; trial registration number not reported.

Unclear - only approx. 20% of patients approached were included in the study. 40% of patients deemed eligible declined to enter study.

Unclear - not reported.

Yes for treatment; unclear for BMD scanning.

Unclear - patient randomised, PCPs not reported.

Feldstein 2006 [47]

Yes

Yes

Yes

Yes

Unclear - protocol not published; trial registration number not reported.

Yes

Yes

Yes

Unclear - patient randomised: 15 primary care clinics involved with 159 PCPs, average one to three patients per PCP.

Davis 2007 [48]

Yes

No

No

Yes

Unclear - protocol not published; trial registration number not reported.

Yes

Yes

Yes for treatment; unclear for BMD scanning.

Unclear - patient randomised, PCPs not reported.

Majumdar 2007 [49]

Yes

Yes

Yes

Yes

Yes for primary outcome; no for secondary outcomes.

Yes

Yes

Yes for treatment; unclear for BMD scanning.

Unclear - possibility of contamination if control and intervention patients on ward at same time.

Solomon 2007 [50]

Unclear

Unclear

Unclear

Yes

Unclear - protocol not published; trial registration number not reported.

Yes

Yes

Yes

Unclear - physician randomised but practices in which they worked not reported on.

Cranney 2008 [51]

Yes

Yes

Yes

Yes

Unclear - protocol not published; trial registration number not reported.

Yes

Yes

Yes

Yes

Majumdar 2008 [52]

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes for treatment; unclear for BMD scanning.

Yes

Miki 2008 [53]

Unclear

Unclear

No

Yes

Unclear - protocol not published; trial registration number not reported.

Unclear - stopped early as deemed unethical to continue following interim analysis.

Yes

Yes

Yes

Rozental 2008 [54]

Unclear

Unclear

Unclear

Yes

Unclear - protocol not published; trial registration number not reported.

Yes

Yes

Yes for treatment; unclear for BMD scanning.

Unclear - patient randomised, PCPs not reported.