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Table 6 Evidence-based clinical/therapeutic practices that could be supported in EQUIP-2:

From: EQUIP: Implementing chronic care principles and applying formative evaluation methods to improve care for schizophrenia: QUERI Series

1. Clozapine for patients with severe psychosis, with the goal of increasing the proportion who receive clozapine (Evidence level1 = 1b, [39]);
2. Wellness intervention for elevated weight, with the goals of increasing the proportion of patients receiving antipsychotic medication with less weight gain potential (Evidence level = 1a, [40]), and increasing the proportion of patients who receive a group-based wellness intervention [41]);
3. Family involvement to improve symptom control and functioning (Evidence level = 1a, [42]), with the goals of increasing the proportion of family members who are involved in developing the patient's treatment plan; and
4. Supported Employment for unemployment (Evidence level = 1b, [43]), with the goal of increasing the proportion of patients (who want to work) receiving evidence-based rehabilitation services that lead to competitive employment.
  1. Evidence Pyramid
  2. 1a: Evidence obtained from meta-analysis of randomized controlled trials (RCTs)
  3. 1b: Evidence obtained from at least 1 RCT
  4. 2a: Evidence obtained from at least 1 well-designed controlled study without randomization
  5. 2b: Evidence obtained from at least 1 other type of well-designed quasi-experimental study
  6. 3: Evidence obtained from well-designed non-experimental descriptive studies, such as comparative studies, correlation studies and case control studies
  7. 4: Evidence obtained from expert committee reports or opinions and/or clinical experience of respected authorities