A pragmatic cluster randomised controlled trial of a Diabetes REcall And Management system: the DREAM trial

Table 3 Self-reported medication data from the patient questionnaire survey.

Drug category	% of subjects taking drug by group		Effect of intervention		Effect of intervention adjusted for a difference between registers
	Control	Intervention	RR	95% CI	RR	95% CI
*Diabetes medication*
Diet alone	46.4	47.0	1.01	0.87, 1.18	1.02	0.89, 1.17
Any oral hypoglycaemic (biguanide, sulphonylurea or thiazolidinediones)	34.0	32.7	0.96	0.81, 1.14	0.96	0.81, 1.14
Sulphonylurea	19.7	18.6	0.94	0.75, 1.18	0.93	0.75, 1.16
Metformin	25.3	24.4	0.96	0.76, 1.22	0.97	0.77, 1.22
Insulin	24.4	26.8	1.10	0.84, 1.43	1.09	0.82, 1.37
*Cardiovascular disease and risk factor management*
Any cardiovascular drug	49.6	45.9	0.92	0.84, 1.01	0.93	0.85, 1.01
Any anti-platelet drug	25.4	22.9	0.90	0.74, 1.10	0.90	0.75, 1.10
Aspirin	31.6	28.5	0.90	0.75, 1.08	0.90	0.75, 1.08
ACE inhibitor	25.0	22.1	0.89	0.75, 1.05	0.89	0.76, 1.05
Drugs primarily used as^a antihypertensives (including ACE/A-G inhibitors)	33.1	30.4	0.92	0.82, 1.03	0.92	0.83, 1.03
Any lipid-lowering	27.4	25.9	0.94	0.78, 1.14	0.95	0.78, 1.15
Statins	27.0	25.0	0.92	0.76, 1.12	0.93	0.77, 1.12
Fibrates	1.0	1.6	1.61	0.61, 4.27	1.59	0.60, 4.18

a. Categories of cardiovascular drugs can be prescribed for more than one purpose (e.g., beta-blockers may be used to treat hypertension but also treat angina), whereas individual drugs within categories (e.g., atenolol) may be better known to be used for a specific purpose. The drugs in this category were known to be used primarily as antihypertensives.

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